A first computational frame for recognizing heparin-binding protein

W Zhu, SS Yuan, J Li, CB Huang, H Lin, B Liao - Diagnostics, 2023 - mdpi.com
Heparin-binding protein (HBP) is a cationic antibacterial protein derived from multinuclear
neutrophils and an important biomarker of infectious diseases. The correct identification of …

Accurately identifying hemagglutinin using sequence information and machine learning methods

X Zou, L Ren, P Cai, Y Zhang, H Ding, K Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Hemagglutinin (HA) is responsible for facilitating viral entry and infection by
promoting the fusion between the host membrane and the virus. Given its significance in the …

HLPpred-Fuse: improved and robust prediction of hemolytic peptide and its activity by fusing multiple feature representation

MM Hasan, N Schaduangrat, S Basith, G Lee… - …, 2020 - academic.oup.com
Motivation Therapeutic peptides failing at clinical trials could be attributed to their toxicity
profiles like hemolytic activity, which hamper further progress of peptides as drug …

Prediction of interactions between viral and host proteins using supervised machine learning methods

RK Barman, S Saha, S Das - PloS one, 2014 - journals.plos.org
Background Viral-host protein-protein interaction plays a vital role in pathogenesis, since it
defines viral infection of the host and regulation of the host proteins. Identification of key viral …

Sequence based prediction of DNA-binding proteins based on hybrid feature selection using random forest and Gaussian naive Bayes

W Lou, X Wang, F Chen, Y Chen, B Jiang, H Zhang - PloS one, 2014 - journals.plos.org
Developing an efficient method for determination of the DNA-binding proteins, due to their
vital roles in gene regulation, is becoming highly desired since it would be invaluable to …

AMPDeep: hemolytic activity prediction of antimicrobial peptides using transfer learning

M Salem, A Keshavarzi Arshadi, JS Yuan - BMC bioinformatics, 2022 - Springer
Background Deep learning's automatic feature extraction has proven to give superior
performance in many sequence classification tasks. However, deep learning models …

[PDF][PDF] Identification of hormone binding proteins based on machine learning methods

JX Tan, SH Li, ZM Zhang, CX Chen, W Chen… - Math. Biosci …, 2019 - aimspress.com
The soluble carrier hormone binding protein (HBP) plays an important role in the growth of
human and other animals. HBP can also selectively and non-covalently interact with …

A web server and mobile app for computing hemolytic potency of peptides

K Chaudhary, R Kumar, S Singh, A Tuknait… - Scientific reports, 2016 - nature.com
Numerous therapeutic peptides do not enter the clinical trials just because of their high
hemolytic activity. Recently, we developed a database, Hemolytik, for maintaining …

[HTML][HTML] Pred-BVP-Unb: Fast prediction of bacteriophage Virion proteins using un-biased multi-perspective properties with recursive feature elimination

M Arif, F Ali, S Ahmad, M Kabir, Z Ali, M Hayat - Genomics, 2020 - Elsevier
Bacteriophage virion proteins (BVPs) are bacterial viruses that have a great impact on
different biological functions of bacteria. They are significantly used in genetic engineering …

Optimizing classification efficiency with machine learning techniques for pattern matching

BA Hamed, OAS Ibrahim, T Abd El-Hafeez - Journal of Big Data, 2023 - Springer
The study proposes a novel model for DNA sequence classification that combines machine
learning methods and a pattern-matching algorithm. This model aims to effectively …