Immunomodulatory effects of granulocyte and monocyte adsorption apheresis as a treatment for patients with ulcerative colitis
N Kashiwagi, K Sugimura, H Koiwai… - Digestive diseases and …, 2002 - Springer
Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …
Clinical evaluation of granulocyte/monocyte apheresis therapy for active ulcerative colitis
K Kanke, M Nakano, H Hiraishi, A Terano - Digestive and liver disease, 2004 - Elsevier
BACKGROUND.: Recent evidence suggests that peripheral blood granulocytes and
monocytes/macrophages have a major role in the exacerbation of ulcerative colitis. AIMS …
monocytes/macrophages have a major role in the exacerbation of ulcerative colitis. AIMS …
Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study
T Shimoyama, K Sawada, N Hiwatashi… - Journal of Clinical …, 2001 - Wiley Online Library
Active ulcerative colitis (UC) is characterized by activation and infiltration of granulocytes
and monocytes/macrophages into the colonic mucosa. The infiltrated leukocytes can cause …
and monocytes/macrophages into the colonic mucosa. The infiltrated leukocytes can cause …
Therapeutic efficacy of granulocyte and monocyte adsorption apheresis in severe active ulcerative colitis
H Hanai, F Watanabe, AR Saniabadi… - Digestive diseases …, 2002 - search.proquest.com
Ulcerative colitis (UC) is a chronic and recurrent inflammatory bowel disease that appears
with varying severity. The disease is associated with activation of the immune system and …
with varying severity. The disease is associated with activation of the immune system and …
Leukocyte adsorptive apheresis for the treatment of active ulcerative colitis: a prospective, uncontrolled, pilot study
H Hanai, F Watanabe, K Takeuchi, T Iida… - Clinical …, 2003 - Elsevier
Background & Aims: Active ulcerative colitis (UC) is characterized by infiltration of activated
granulocytes and monocytes/macrophages (GM) within the large bowel mucosa. GM are …
granulocytes and monocytes/macrophages (GM) within the large bowel mucosa. GM are …
Granulocyte apheresis in inflammatory bowel disease: possible mechanisms of effect
BJ Rembacken, HE Newbould… - Therapeutic …, 1998 - Wiley Online Library
We have studied the effects of granulocyte apheresis in 18 patients with ulcerative colitis
and 6 with Crohn's disease who had failed to respond to conventional therapy. Patients …
and 6 with Crohn's disease who had failed to respond to conventional therapy. Patients …
[HTML][HTML] Safety and clinical efficacy of granulocyte and monocyte adsorptive apheresis therapy for ulcerative colitis
T Yamamoto, S Umegae… - World Journal of …, 2006 - ncbi.nlm.nih.gov
Active ulcerative colitis (UC) is frequently associated with infiltration of a large number of
leukocytes into the bowel mucosa. Therefore, removal of activated circulating leukocytes by …
leukocytes into the bowel mucosa. Therefore, removal of activated circulating leukocytes by …
Adacolumn selective leukocyte adsorption apheresis in patients with active ulcerative colitis: clinical efficacy, effects on plasma IL-8, and expression of Toll-like …
H Aoki, K Nakamura, Y Yoshimatsu, Y Tsuda… - Digestive diseases and …, 2007 - Springer
Adacolumn selective granulocyte and monocyte apheresis (GMA) depletes activated
leukocytes in patients with ulcerative colitis (UC). However, this per se cannot fully explain …
leukocytes in patients with ulcerative colitis (UC). However, this per se cannot fully explain …
A retrospective search for predictors of clinical response to selective granulocyte and monocyte apheresis in patients with ulcerative colitis
Y Suzuki, N Yoshimura, K Fukuda, K Shirai… - Digestive diseases and …, 2006 - Springer
Recently, selective granulocytapheresis (Adacolumn) has appeared as a new treatment for
patients with inflammatory bowel disease. This study sought to determine predictors of …
patients with inflammatory bowel disease. This study sought to determine predictors of …
A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitis
BE Sands, WJ Sandborn, B Feagan, R Löfberg, T Hibi… - Gastroenterology, 2008 - Elsevier
BACKGROUND & AIMS: Activated granulocytes and monocytes/macrophages are
implicated in the pathogenesis of ulcerative colitis. Open-label studies and clinical …
implicated in the pathogenesis of ulcerative colitis. Open-label studies and clinical …
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