Many drugs currently used in clinics to treat different diseases show low solubilities in
aqueous solutions and must be then administered with the aid of organic solvents within the …

In this work, we designed a drug delivery nanosystem based on oil-in-water Pluronic F127
nanomicelles to encapsulate and control the release of the antineoplasic drug carfilzomib …

Lately, nanoemulsions loaded with hydrophobic drugs have been successfully developed to
improve the treatment of several global diseases. On this subject, a detailed study of the …

Aqueous solubility of an active pharmaceutical ingredient (API) is a determining factor that
has a direct impact on formulation strategies and overall bioavailability. Fabrication of …

The main goal of this study was to predict the capacity of the hybrid nanoparticles based on
poli (lactic-co-glycolic acid) PLGA-vegetable oil to encapsulate and then to release a …

Lipophilic compounds constitute a majority of therapeutics in the pipeline of drug discovery.
Despite possessing enhanced efficacy and permeability, some of these drugs suffer poor …

Nanoemulsions are a rapidly growing drug delivery technology capable of increasing a
drug's aqueous solubility and stability. A novel oil‐in‐water nanoemulsion using a polymer …

The development of optimized carrier materials for the encapsulation of new high-potency
drugs is frequently hampered by the need for trial-and-error experiments. Combining …

The association of an active principle with a nanocarrier is known to improve its stability and
protect it from external factors. Nevertheless, loading of nanoparticles with highly hydrophilic …

In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability,
poor drug absorption, and inability to achieve the therapeutic concentration in blood. The …