[HTML][HTML] StartReact effects support different pathophysiological mechanisms underlying freezing of gait and postural instability in Parkinson's disease

J Nonnekes, D de Kam, LBO Nijhuis, K van Geel… - PLoS …, 2015 - journals.plos.org
Introduction The pathophysiology underlying postural instability in Parkinson's disease is
poorly understood. The frequent co-existence with freezing of gait raises the possibility of …

Reduced StartReact effect and freezing of gait in Parkinson's disease: two of a kind?

J Nonnekes, ACH Geurts, LB Oude Nijhuis… - Journal of …, 2014 - Springer
Freezing of gait (FOG) is a disabling feature of Parkinson's disease. Emerging evidence
suggests that dysfunction of the pedunculopontine nucleus (PPN) and pontomedullary …

Dynamics of postural control in Parkinson patients with and without symptoms of freezing of gait

O Pelykh, AM Klein, K Bötzel, Z Kosutzka, J Ilmberger - Gait & Posture, 2015 - Elsevier
Background It has been suggested that dynamical measures such as sample entropy may
be more appropriate than conventional measures when analyzing time series data such as …

Which aspects of postural control differentiate between patients with Parkinson's disease with and without freezing of gait?

G Vervoort, E Nackaerts, F Mohammadi… - Parkinson's …, 2013 - Wiley Online Library
This exploratory study aimed to identify which aspects of postural control are able to
distinguish between subgroups of patients with Parkinson's disease (PD) and controls …

[HTML][HTML] Recovery from multiple APAs delays gait initiation in Parkinson's disease

RG Cohen, JG Nutt, FB Horak - Frontiers in human neuroscience, 2017 - frontiersin.org
Background: Freezing of gait in Parkinson's disease (PD) has been linked with deficits in
inhibitory control, but causal mechanisms are not established. Freezing at gait initiation (start …

Freezing of gait in Parkinson's disease reflects a sudden derangement of locomotor network dynamics

NG Pozzi, A Canessa, C Palmisano, J Brumberg… - Brain, 2019 - academic.oup.com
Freezing of gait is a disabling symptom of Parkinson's disease that causes a paroxysmal
inability to generate effective stepping. The underlying pathophysiology has recently …

Balancing between the two: Are freezing of gait and postural instability in Parkinson's disease connected?

EMJ Bekkers, BW Dijkstra, E Heremans… - Neuroscience & …, 2018 - Elsevier
Postural instability and freezing of gait (FoG) are key features of Parkinson's disease (PD)
closely related to falls. Growing evidence suggests that co-existing postural deficits could …

Generalized motor inhibitory deficit in Parkinson's disease patients who freeze

PG Bissett, GD Logan, NC van Wouwe… - Journal of neural …, 2015 - Springer
Freezing of gait is a disabling symptom of Parkinson's disease (PD) that involves failure to
initiate and continue motor activity appropriately. PD disrupts fronto-basal ganglia circuitries …

A block to pre-prepared movement in gait freezing, relieved by pedunculopontine nucleus stimulation

W Thevathasan, A Pogosyan, JA Hyam, N Jenkinson… - Brain, 2011 - academic.oup.com
Gait freezing and postural instability are disabling features of Parkinsonian disorders,
treatable with pedunculopontine nucleus stimulation. Both features are considered deficits of …

Impaired weight-shift amplitude in people with Parkinson's disease with freezing of gait

BW Dijkstra, M Gilat, LE Cofré Lizama… - Journal of …, 2021 - content.iospress.com
Background: People with Parkinson's disease and freezing of gait (FOG; freezers) suffer
from pronounced postural instability. However, the relationship between these phenomena …