[HTML][HTML] The role of biomarkers in the management of colorectal liver metastases

DB Hewitt, ZJ Brown, TM Pawlik - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer remains one of the most significant sources of cancer-
related morbidity and mortality worldwide. The liver is the most common site of metastatic …

Emerging paradigms in the treatment of liver metastases in colorectal cancer

A Alhumaid, Z AlYousef, HA Bakhsh… - Critical Reviews in …, 2018 - Elsevier
Efforts to combat colorectal cancer have benefited from improved screening and
surveillance, which facilitates early detection. The survival rate associated with diagnosis at …

[HTML][HTML] Colorectal cancer liver metastasis: evolving paradigms and future directions

LR Zarour, S Anand, KG Billingsley, WH Bisson… - Cellular and molecular …, 2017 - Elsevier
In patients with colorectal cancer (CRC) that metastasizes to the liver, there are several key
goals for improving outcomes including early detection, effective prognostic indicators of …

[HTML][HTML] Colorectal cancer liver metastases: Genomics and biomarkers with focus on local therapies

Y Kitsel, T Cooke, V Sotirchos, CT Sofocleous - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a leading cause of death among cancer
patients, and the liver is the most common visceral metastatic site. Despite promising …

Colorectal liver metastases: does the future of precision medicine lie in genetic testing?

C Barbon, GA Margonis, N Andreatos, N Rezaee… - Journal of …, 2018 - Elsevier
Colorectal liver metastases (CRLM) present an important clinical challenge in both surgical
and medical oncology. Despite improvements in management, survival among patients …

[HTML][HTML] Tailored systemic therapy for colorectal cancer liver metastases

C Czauderna, K Luley, N von Bubnoff… - International Journal of …, 2021 - mdpi.com
Liver metastases are the most common site of metastatic spread in colorectal cancer.
Current treatment approaches involve effective systemic therapies in combination with …

Biomarkers in colorectal liver metastases: Rising complexity and unknown clinical significance?

MK Diener, S Fichtner‐Feigl - Annals of Gastroenterological …, 2021 - Wiley Online Library
Surgical resection of the liver is the standard treatment for colorectal liver metastases, but
70% of patients still experience recurrence, resulting in limited survival. Molecular …

[HTML][HTML] Proteomic profiling and biomarker discovery in colorectal liver metastases

GYM Wong, C Diakos, TJ Hugh, MP Molloy - International Journal of …, 2022 - mdpi.com
Colorectal liver metastases (CRLM) are the leading cause of death among patients with
metastatic colorectal cancer (CRC). As part of multimodal therapy, liver resection is the …

[HTML][HTML] Can molecular biomarkers replace a clinical risk score for resectable colorectal liver metastasis?

T Veen, K Søreide - World Journal of Gastrointestinal Oncology, 2017 - ncbi.nlm.nih.gov
In resectable colorectal liver metastasis (CRLM) the role and use of molecular biomarkers is
still controversial. Several biomarkers have been linked to clinical outcomes in CRLM, but …

Molecular prognostic markers in resectable colorectal liver metastases: a systematic review

CP Neal, G Garcea, H Doucas, MM Manson… - European journal of …, 2006 - Elsevier
BACKGROUND: Determination of prognosis in patients with resectable colorectal liver
metastases (CLM) is desirable in order to improve case selection for surgery and tailor …