A well‐documented amygdala‐dorsomedial prefrontal circuit is theorized to promote
attention to threat (“threat vigilance”). Prior research has implicated a relationship between …

Findings from fear-conditioning studies in rats and functional neuroimaging with human
volunteers have led to the suggestion that the amygdala is involved in the preattentive …

Aversive events are typically more debilitating when they occur unpredictably than
predictably. Studies in humans and animals indicate that predictable and unpredictable …

Background: Neuroimaging research has traditionally explored fear and anxiety in response
to discrete threat cues (eg, during fear conditioning). However, anxiety is a sustained …

Many of the same regions of the human brain are activated during conscious attention to
signals of fear and in the absence of awareness for these signals. The neural mechanisms …

Rodent and human studies have implicated an amygdala-prefrontal circuit during threat
processing. One possibility is that while amygdala activity underlies core features of anxiety …

Background Anxiety produced by environmental threats can impair goal-directed processing
and is associated with a range of psychiatric disorders, particularly when aversive events …

Threat-related stimuli are strong competitors for attention, particularly in anxious individuals.
We used functional magnetic resonance imaging (fMRI) with healthy human volunteers to …

Recent theories distinguish anxiety from fear in the brain. Anxiety is associated with
activation in ventromedial prefrontal cortex and hippocampus, while fear is associated with …

Background A well-characterized amygdala–dorsomedial prefrontal circuit is thought to be
crucial for threat vigilance during anxiety. However, engagement of this circuitry within …