Paracetamol (acetaminophen) is generally considered to be a weak inhibitor of the
synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to …

Paracetamol and salicylate are weak inhibitors of both isolated cyclooxygenase-1 (COX-1)
and COX-2 but are potent inhibitors of prostaglandin (PG) synthesis in intact cells if low …

Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

BACKGROUND: Paracetamol is a potent analgesic and antipyretic drug, but has only weak
anti-inflammatory activity. Unlike aspirin-like drugs, paracetamol does not damage the …

Paracetamol (acetaminophen) is undoubtedly one of the most widely used drugs worldwide.
As an over-the-counter medication, paracetamol is the standard and first-line treatment for …

Acetaminophen, also known as paracetamol, is a nonsteroidal anti-inflammatory drug with
potent antipyretic and analgesic actions but with very weak anti-inflammatory activity. When …

Aspirin exerts its analgesic, antipyretic and anti-inflammatory actions by inhibiting the
enzyme cyclooxygenase and thus preventing the formation and release of prostaglandins …

Acetaminophen has similar analgesic and antipyretic properties to nonsteroidal
antiinflammatory drugs (NSAIDs), which act via inhibition of cyclooxygenase enzymes …

Acetaminophen (INN, paracetamol) possesses highly selective analgesic and antipyretic
effects that result from its inhibitory actions on the synthesis of prostaglandins (PGs). PGs are …

For more than three decades, acetaminophen (INN, paracetamol) has been claimed to be
devoid of significant inhibition of peripheral prostanoids. Meanwhile, attempts to explain its …