Microplastic-induced gut microbiota and serum metabolic disruption in Sprague-Dawley rats

N Zhao, M Zhao, H Jin - Environmental Pollution, 2023 - Elsevier
Toxic effects of exposure to microplastics (MPs) on living organisms and humans have
attracted global concern. However, most previous studies exposed animals to only one type …

Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice

Y Jin, L Lu, W Tu, T Luo, Z Fu - Science of the total environment, 2019 - Elsevier
Microplastics (MPs), which are new environmental pollutants with a diameter of< 5 mm, have
received wide attention in recent years. However, there are still very limited data regarding …

Underestimated health risks: Dietary restriction magnify the intestinal barrier dysfunction and liver injury in mice induced by polystyrene microplastics

W Lv, Y Shen, S Xu, B Wu, Z Zhang, S Liu - Science of The Total …, 2023 - Elsevier
Microplastics (MPs) have gained significant attention due to their widespread presence in
the environment. While studies have been conducted to investigate the risks associated with …

Polystyrene microplastics induce size-dependent multi-organ damage in mice: Insights into gut microbiota and fecal metabolites

Z Zhang, W Chen, H Chan, J Peng, P Zhu, J Li… - Journal of Hazardous …, 2024 - Elsevier
Particle size is one of the most important factors in determining the biological toxicity of
microplastics (MPs). In this study, we attempted to examine the systemic toxicity of …

Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice

L Lu, Z Wan, T Luo, Z Fu, Y Jin - Science of the total environment, 2018 - Elsevier
Microplastic (MP) has become a concerning global environmental problem. It is toxic to
aquatic organisms and can spread through the food chain to ultimately pose a threat to …

Long-term exposure to environmentally relevant doses of large polystyrene microplastics disturbs lipid homeostasis via bowel function interference

Y Deng, H Chen, Y Huang, Y Zhang… - … science & technology, 2022 - ACS Publications
The question of whether long-term chronic exposure to microplastics (MPs) could induce
dose-and size-dependent adverse effects in mammals remains controversial and poorly …

[HTML][HTML] A comparative study in healthy and diabetic mice followed the exposure of polystyrene microplastics: differential lipid metabolism and inflammation reaction

S Liu, Z Wang, Q Xiang, B Wu, W Lv, S Xu - … and Environmental Safety, 2022 - Elsevier
Human exposure to microplastics (MPs) continues to occur due to ingestion of contaminated
food, water and air. Intake of MPs can pose potential health risks by interfering with the …

[HTML][HTML] Polystyrene microplastic exposure induces insulin resistance in mice via dysbacteriosis and pro-inflammation

D Huang, Y Zhang, J Long, X Yang, L Bao… - Science of The Total …, 2022 - Elsevier
Microplastics (MPs) as emerging contaminants have become a global environmental
problem. However, studies on the effects of MPs on metabolic diseases remain limited …

Microplastic: A potential threat to human and animal health by interfering with the intestinal barrier function and changing the intestinal microenvironment

Z Huang, Y Weng, Q Shen, Y Zhao, Y Jin - Science of the Total Environment, 2021 - Elsevier
Plastics are widely used in many fields due to their stable physical and chemical properties,
and their global production and usage increase significantly every year, which leads to the …

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

L Lu, T Luo, Y Zhao, C Cai, Z Fu, Y Jin - Science of the Total Environment, 2019 - Elsevier
Microplastics (MPs) has gradually become a global environmental pollution problem and
may harm human and animal health. In recent years, a large number of studies had shown …