Understanding the biological basis of autofluorescence imaging for oral cancer detection: high-resolution fluorescence microscopy in viable tissue

I Pavlova, M Williams, A El-Naggar… - Clinical Cancer …, 2008 - AACR
Purpose: Autofluorescence imaging is increasingly used to noninvasively identify neoplastic
oral cavity lesions. Improving the diagnostic accuracy of these techniques requires a better …

Advances in fluorescence imaging techniques to detect oral cancer and its precursors

D Shin, N Vigneswaran, A Gillenwater… - Future …, 2010 - Future Medicine
Oral cancer is a significant health problem in the USA and throughout the world. Most oral
cancer patients are diagnosed at a late stage, when treatment is less successful and …

The status of in vivo autofluorescence spectroscopy and imaging for oral oncology

DCG De Veld, MJH Witjes, H Sterenborg… - Oral oncology, 2005 - Elsevier
Autofluorescence spectroscopy and imaging have been studied for the early detection and
classification of (pre) malignancies of the oral mucosa. In the present review we will give an …

Effectiveness of autofluorescence to identify suspicious oral lesions—a prospective, blinded clinical trial

FP Koch, PW Kaemmerer, S Biesterfeld… - Clinical oral …, 2011 - Springer
Regular screening through white light inspection of the entire oral mucosa is the most
important examination method to identify precancerous lesions and early oral carcinoma …

Autofluorescence imaging and spectroscopy of normal and malignant mucosa in patients with head and neck cancer

CS Betz, M Mehlmann, K Rick, H Stepp… - Lasers in Surgery …, 1999 - Wiley Online Library
Abstract Background and Objective An early detection of oral cancer might improve the
patient's prognosis. We present preliminary results of autofluorescence photodetection of …

Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence

A Gillenwater, R Jacob, R Ganeshappa… - … –head & neck …, 1998 - jamanetwork.com
Objective To evaluate the clinical potential of fluorescence spectroscopy (a noninvasive
technique for assessing the chemical and morphologic composition of tissue) for in vivo …

Autofluorescence characteristics of oral mucosa

DR Ingrams, JK Dhingra, K Roy, DF Perrault Jr… - Head & …, 1997 - Wiley Online Library
Background The fluorescence characteristics of tissues depend upon their biochemical
composition and histomorphological architecture, both of which undergo a change during …

Vision enhancement system for detection of oral cavity neoplasia based on autofluorescence

E Svistun, R Alizadeh‐Naderi… - Head & Neck …, 2004 - Wiley Online Library
Background. Early detection of squamous cell carcinoma (SCC) in the oral cavity can
improve survival. It is often difficult to distinguish neoplastic and benign lesions with …

Efficacy of tissue autofluorescence imaging (VELScope) in the visualization of oral mucosal lesions

CS Farah, L McIntosh, A Georgiou… - Head & neck, 2012 - Wiley Online Library
Background Technology that highlights potentially malignant oral lesions in a highly
sensitive and specific manner will aid clinicians in early diagnosis of these conditions. This …

Autofluorescence characteristics of healthy oral mucosa at different anatomical sites

DCG de Veld, M Skurichina, MJH Witjes… - Lasers in Surgery …, 2003 - Wiley Online Library
Abstract Background and Objectives Autofluorescence spectroscopy is a promising tool for
oral cancer detection. Its reliability might be improved by using a reference database of …