Regulatory T cells license macrophage pro-resolving functions during atherosclerosis regression
Rationale: Regression of atherosclerosis is an important clinical goal; however, the
pathways that mediate the resolution of atherosclerotic inflammation and reversal of plaques …
pathways that mediate the resolution of atherosclerotic inflammation and reversal of plaques …
Differential effects of regulatory T cells on the initiation and regression of atherosclerosis
OBJECTIVE: Regulatory T cells (Tregs) play an important role in the regulation of T cell-
mediated immune responses through suppression of T cell proliferation and cytokine …
mediated immune responses through suppression of T cell proliferation and cytokine …
Regulatory T cells as a new therapeutic target for atherosclerosis
H Ou, B Guo, Q Liu, Y Li, Z Yang, W Feng… - Acta Pharmacologica …, 2018 - nature.com
Atherosclerosis is an autoimmune disease caused by self-and non-self-antigens
contributing to excessive activation of T and B cell immune responses. These responses …
contributing to excessive activation of T and B cell immune responses. These responses …
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential
Atherosclerosis is a chronic inflammatory disease that is mediated by innate and adaptive
immune responses. The disease is characterized by sub-endothelial accumulation and …
immune responses. The disease is characterized by sub-endothelial accumulation and …
Treating atherosclerosis with regulatory T cells
AC Foks, AH Lichtman, J Kuiper - Arteriosclerosis, thrombosis, and …, 2015 - Am Heart Assoc
Regulatory T cells (Tregs) play an important role in the regulation of T-cell–mediated
immune responses through suppression of T-cell proliferation and secretion of inhibitory …
immune responses through suppression of T-cell proliferation and secretion of inhibitory …
Mechanisms of disease: the evolving role of regulatory T cells in atherosclerosis
J George - Nature Clinical Practice Cardiovascular Medicine, 2008 - nature.com
Atherosclerosis and related complications still represent the major cause of morbidity and
mortality in the western world. The mechanisms that govern the progression and …
mortality in the western world. The mechanisms that govern the progression and …
Dynamic changes in regulatory T cells are linked to levels of diet-induced hypercholesterolemia
E Maganto-García, ML Tarrio, N Grabie, D Bu… - Circulation, 2011 - Am Heart Assoc
Background—Regulatory T cells (Treg) are present in atherosclerotic lesions and can
modulate disease. In this study we characterized changes in Treg responses associated …
modulate disease. In this study we characterized changes in Treg responses associated …
Getting to the heart of the matter: the role of regulatory T-cells (Tregs) in cardiovascular disease (CVD) and atherosclerosis
CJ Albany, SC Trevelin, G Giganti, G Lombardi… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular diseases (CVD) are the leading cause of mortality worldwide.
Atherosclerosis is directly associated with CVD and is characterized by slow progressing …
Atherosclerosis is directly associated with CVD and is characterized by slow progressing …
Statins induce the accumulation of regulatory T cells in atherosclerotic plaque
X Meng, K Zhang, J Li, M Dong, J Yang, G An, W Qin… - Molecular …, 2012 - Springer
Abstract CD4+ CD25+ regulatory T cells (Tregs) mediate immune suppression and prevent
autoimmune disorders. Recently, Tregs were found to present in atherosclerotic lesions and …
autoimmune disorders. Recently, Tregs were found to present in atherosclerotic lesions and …
Cytokine network and T cell immunity in atherosclerosis
Atherosclerosis is a chronic inflammatory disease of the arterial wall where both innate and
adaptive immune responses contribute to disease initiation and progression. Recent studies …
adaptive immune responses contribute to disease initiation and progression. Recent studies …
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