Synaptic vesicle release regulates pre-myelinating oligodendrocyte-axon interactions in a neuron subtype-specific manner
JR Gronseth, HN Nelson, TL Johnson… - Frontiers in Cellular …, 2024 - frontiersin.org
Oligodendrocyte-lineage cells are central nervous system (CNS) glia that perform multiple
functions including the selective myelination of some but not all axons. During myelination …
functions including the selective myelination of some but not all axons. During myelination …
Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth
RG Almeida, JM Williamson, ME Madden, JJ Early… - Current Biology, 2021 - cell.com
Myelination of axons by oligodendrocytes enables fast saltatory conduction.
Oligodendrocytes are responsive to neuronal activity, which has been shown to induce …
Oligodendrocytes are responsive to neuronal activity, which has been shown to induce …
Oligodendrocyte Development in the Absence of Their Target Axons In Vivo
Oligodendrocytes form myelin around axons of the central nervous system, enabling
saltatory conduction. Recent work has established that axons can regulate certain aspects of …
saltatory conduction. Recent work has established that axons can regulate certain aspects of …
Individual neuronal subtypes control initial myelin sheath growth and stabilization
HN Nelson, AJ Treichel, EN Eggum, MR Martell… - Neural …, 2020 - Springer
Background In the developing central nervous system, pre-myelinating oligodendrocytes
sample candidate nerve axons by extending and retracting process extensions. Some …
sample candidate nerve axons by extending and retracting process extensions. Some …
Synaptic proteins expressed by oligodendrocytes mediate CNS myelination
AN Hughes, B Appel - bioRxiv, 2018 - biorxiv.org
Oligodendrocytes ensheath neuronal axons with myelin, a proteolipid-rich membrane that
increases conduction velocity and provides trophic support. Our lab and others have …
increases conduction velocity and provides trophic support. Our lab and others have …
Individual neuronal subtypes exhibit diversity in CNS myelination mediated by synaptic vesicle release
S Koudelka, MG Voas, RG Almeida, M Baraban… - Current Biology, 2016 - cell.com
Regulation of myelination by oligodendrocytes in the CNS has important consequences for
higher-order nervous system function (eg,[1–4]), and there is growing consensus that …
higher-order nervous system function (eg,[1–4]), and there is growing consensus that …
Can't wait to myelinate
TD Glenn, WS Talbot - Developmental Cell, 2013 - cell.com
Oligodendrocytes myelinate axons in the central nervous system (CNS). In this issue of
Developmental Cell, Czopka et al.(2013) shed light on the temporal control of myelination by …
Developmental Cell, Czopka et al.(2013) shed light on the temporal control of myelination by …
Synaptic vesicle fusion along axons is driven by myelination and subsequently accelerates sheath growth in an activity-regulated manner
RG Almeida, JM Williamson, ME Madden, JJ Early… - BioRxiv, 2020 - biorxiv.org
To study activity-regulated myelination, we imaged synaptic vesicle fusion along single
axons in living zebrafish, and found, surprisingly, that axonal synaptic vesicle fusion is …
axons in living zebrafish, and found, surprisingly, that axonal synaptic vesicle fusion is …
Emerging concepts in oligodendrocyte and myelin formation, inputs from the zebrafish model
M Masson, B Nait‐Oumesmar - Glia, 2023 - Wiley Online Library
Oligodendrocytes (OLs) are the myelinating cells of the central nervous system (CNS), which
are derived from OL precursor cells. Myelin insulates axons allowing the saltatory …
are derived from OL precursor cells. Myelin insulates axons allowing the saltatory …
A subset of oligodendrocyte lineage cells interact with the developing dorsal root entry zone during its genesis
LA Green, RM Gallant, JP Brandt, EL Nichols… - Frontiers in Cellular …, 2022 - frontiersin.org
Oligodendrocytes are the myelinating cell of the CNS and are critical for the functionality of
the nervous system. In the packed CNS, we know distinct profiles of oligodendrocytes are …
the nervous system. In the packed CNS, we know distinct profiles of oligodendrocytes are …