Autism is a common and complex neurologic disorder whose scientific underpinnings have
begun to be established in the past decade. The essence of this breakthrough has been a …

Autism spectrum disorder (ASD) is a constellation of neurodevelopmental presentations with
high heritability and both phenotypic and genetic heterogeneity. To date, mutations in …

Highlights•High throughput genomic methods are rapidly increasing the pool of ASD
genes.•Heterogeneity, pleiotropy, and brain complexity complicate translation to …

Autism spectrum disorder (ASD) is a highly heritable neurodevelopmental condition that is
among the most devastating disorders of childhood in terms of prevalence, morbidity …

Autism spectrum disorders (ASDs) are neurodevelopmental conditions characterized by
impairments in social interaction, communication, and the presence of restricted, repetitive …

Recent advances in understanding the genetic architecture of autism spectrum disorder
have allowed for unprecedented insight into its biological underpinnings. New studies have …

Autism spectrum disorders (ASD) are important neuropsychiatric disorders, currently
estimated to affect approximately 1% of children, with considerable emotional and financial …

Autism is a clinically and genetically heterogeneous neurodevelopmental disorder. Although
multiple genes, risk alleles and copy number variants (CNVs) have been implicated in ASD …

The extreme genetic heterogeneity of autism spectrum disorder (ASD) represents a major
challenge. Recent advances in genetic screening and systems biology approaches have …

Autism spectrum disorder (ASD) has been long known to have substantial genetic etiology.
Much research has attempted to identify specific genes contributing to ASD risk with the goal …