The conclusive evidence supporting a role for NK cells in defense against viruses has been
obtained under conditions of NK cell deficiencies prior to infections. NK cell proliferation can …

NK cells contribute to innate defense during certain viral infections, but the mechanisms for
their regulation and delivery of antiviral effects are incompletely understood. A second NK …

Increasing evidence indicates the importance of human natural killer (NK) cells in the
immune response against certain viral infections. In the present article, we summarize …

Natural killer (NK) cells play a crucial role in controlling viral infections. The ability to kill
infected cells without prior immunization, yet being tolerant to self, healthy cells, depends on …

Highlights•NK cells generate long-lived antigen-specific memory cells.•NK cells regulate
viral load and cytokine production of innate immune cells.•NK cells indirectly modulate …

Hepatitis C virus (HCV) infects over 170 million people in the world. While a minority of
individuals are able to naturally clear this hepatotropic virus using their immune system …

Natural killer cells constitute a phenotypically diverse population of innate lymphoid cells
with a broad functional spectrum. Classically defined as cytotoxic lymphocytes with the …

NK cells show cytotoxicity and cytokine production upon recognition of virus‐infected cells
and play an important role in conferring protective immunity against virus infection. Patients …

An array of inhibitory and activating receptors initially identified on NK cells are also
expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK …

NK cells have an important role in innate immune responses, particularly in anti-viral
immunity. Recent studies have revealed a molecular basis for NK cell recognition of virus …