Marijuana is a widely used psychoactive substance in the US and medical and recreational
legalization has risen over the past decade. Despite the growing number of individuals …

Cannabis use is highly prevalent and is associated with adverse and beneficial effects. To
better understand the full spectrum of health consequences, biomarkers that accurately …

Background Marijuana is the third most commonly used drug in the USA and efforts to
legalize it for medical and recreational use are growing. Despite the increase in use …

Numerous DNA methylation (DNAm) biomarkers of cigarette smoking have been identified
in peripheral blood studies, but because of tissue specificity, blood-based studies may not …

DNA methylation may be one of the mechanisms by which alcohol consumption is
associated with the risk of disease. We conducted a large‐scale, cross‐sectional, genome …

Cannabis use is of increasing public health interest globally. Here we examined the effect of
heavy cannabis use, with and without tobacco, on genome-wide DNA methylation in a …

Cigarette smoking has been associated with epigenetic alterations that may be reversible
upon cessation. As the most-studied epigenetic modification, DNA methylation is strongly …

Background Epigenome-wide profiling of DNA methylation pattern with respect to tobacco
smoking has given rise to a new measure of smoking exposure. We investigated the …

We conducted a genome-wide association study of blood DNA methylation and smoking,
attempted replication of previously discovered associations, and assessed the reversibility of …

We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions …