Targeting Trojan Horse leukocytes for HIV prevention

DJ Anderson, JA Politch, AM Nadolski, CD Blaskewicz… - Aids, 2010 - journals.lww.com
Targeting Trojan Horse leukocytes for HIV prevention : AIDS Targeting Trojan Horse leukocytes
for HIV prevention : AIDS Log in or Register Subscribe to journalSubscribe Get new issue …

[HTML][HTML] Engineering CAR T cells to target the HIV reservoir

W Mu, MA Carrillo, SG Kitchen - Frontiers in cellular and infection …, 2020 - frontiersin.org
The HIV reservoir remains to be a difficult barrier to overcome in order to achieve a
therapeutic cure for HIV. Several strategies have been developed to purge the reservoir …

[HTML][HTML] The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection

M Cavrois, J Neidleman, WC Greene - PLoS pathogens, 2008 - journals.plos.org
To ensure their survival, microbial pathogens have evolved diverse strategies to subvert
host immune defenses. The human retrovirus HIV-1 has been proposed to hijack the natural …

Hematopoietic stem/precursor cells as HIV reservoirs

LA McNamara, KL Collins - Current Opinion in HIV and AIDS, 2011 - journals.lww.com
To eradicate HIV infection, it will be necessary to purge all viral reservoirs in the host. The
findings highlighted here suggest that multipotent hematopoietic progenitor cells and …

HIV: current opinion in escapology

P Klenerman, Y Wu, R Phillips - Current opinion in microbiology, 2002 - Elsevier
Much recent work strongly supports the hypothesis that CD8+ T lymphocytes (CTLs) exert
important immune control over HIV and so are a major selective force in its evolution. We …

[图书][B] Moving mountains: The race to treat global AIDS

AC d'Adesky - 2006 - books.google.com
In dispatches written from around the world, Anne-christine d'Adesky reports on the greatest
challenge facing us today: the global effort to provide life-saving medicines and care to 40 …

Reconsidering targeted toxins to eliminate HIV infection: you gotta have HAART

EA Berger, B Moss, I Pastan - Proceedings of the National …, 1998 - National Acad Sciences
The success of highly active anti-retroviral therapy (HAART) has inspired new concepts for
eliminating HIV from infected individuals. A major obstacle is the persistence of long-lived …

Building an HIV-proof immune system

J Cohen - Science, 2007 - science.org
Published by AAAS of the modified stem cells, presumably because they produced progeny
that survived. The strategy looked promising enough that J&J moved ahead with a larger …

Macrophage activation and HIV infection: can the Trojan horse turn into a fortress?

G Herbein, A Coaquette… - Current molecular …, 2002 - ingentaconnect.com
Macrophages are infected early during HIV infection and are thought to play the role of a
Trojan horse by spreading infection in tissues. Most recent studies point out to a more …

Exploring how to get at--and eradicate--hidden HIV

J Cohen - Science, 1998 - science.org
D edham, M assachusetts—Arthur Ammann, head of the American Foundation for AIDS
Research (AmFAR), placed a small placard next to a slide projector sitting in the back of a …