Intranasal administration of dauricine loaded on graphene oxide: multi-target therapy for Alzheimer's disease
K Wang, L Wang, L Chen, C Peng, B Luo, J Mo… - Drug Delivery, 2021 - Taylor & Francis
Alzheimer's disease (AD) is a degenerative disease of the central nervous system
characterized by progressive cognitive and memory-related impairment. However, current …
characterized by progressive cognitive and memory-related impairment. However, current …
Graphene oxide ameliorates the cognitive impairment through inhibiting PI3K/Akt/mTOR pathway to induce autophagy in AD mouse model
F Chu, K Li, X Li, L Xu, J Huang, Z Yang - Neurochemical Research, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease of the central nervous system
characterised by cognitive impairment. Its major pathological feature is the deposition of β …
characterised by cognitive impairment. Its major pathological feature is the deposition of β …
Graphene oxide enhances β-amyloid clearance by inducing autophagy of microglia and neurons
X Li, K Li, F Chu, J Huang, Z Yang - Chemico-Biological Interactions, 2020 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disease, and its pathogenesis is
closely related to β-amyloid (Aβ) peptide. The deposition of Aβ in the brain due to impaired …
closely related to β-amyloid (Aβ) peptide. The deposition of Aβ in the brain due to impaired …
Astragaloside IV ameliorates cognitive impairment and neuroinflammation in an oligomeric Aβ induced Alzheimer's disease mouse model via inhibition of microglial …
F Chen, D Yang, XY Cheng, H Yang… - Biological and …, 2021 - jstage.jst.go.jp
Microglial activation and neuroinflammation induced by amyloid β (Aβ) play pivotal roles in
Alzheimer's disease (AD) pathogenesis. Astragaloside IV (AS-IV) is one of the major active …
Alzheimer's disease (AD) pathogenesis. Astragaloside IV (AS-IV) is one of the major active …
Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer's disease via inhibiting NF-κB signaling pathway
L He, J Sun, Z Miao, S Chen, G Yang - Heliyon, 2023 - cell.com
The inflammatory process plays a significant role in the pathophysiology of Alzheimer's
disease (AD). Anti-neuroinflammatory cascade is now considered an important measure for …
disease (AD). Anti-neuroinflammatory cascade is now considered an important measure for …
[HTML][HTML] Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice
J Zhang, S Zhu, P Jin, Y Huang, Q Dai, Q Zhu, P Wei… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Graphene oxide (GO) based nanomaterials have shown potential for the
diagnosis and treatment of amyloid-β (Aβ)-related diseases, mainly on Alzheimer's disease …
diagnosis and treatment of amyloid-β (Aβ)-related diseases, mainly on Alzheimer's disease …
Neuroprotective effects of a biodegradable poly (lactic-co-glycolic acid)-ginsenoside Rg3 nanoformulation: a potential nanotherapy for Alzheimer's disease?
It is well established that overproduction and accumulation of the β-amyloid (Aβ) peptide 1–
42 (Aβ (1–42)) is a trigger of the pathological cascade in Alzheimer's disease (AD) that …
42 (Aβ (1–42)) is a trigger of the pathological cascade in Alzheimer's disease (AD) that …
Exploring the neuroprotective potential of rosiglitazone embedded nanocarrier system on streptozotocin induced mice model of Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder imposing great threat to an
individual's cognitive capability. Mounting evidence suggests that type 2 diabetes mellitus …
individual's cognitive capability. Mounting evidence suggests that type 2 diabetes mellitus …
Nose-to-brain delivery of 18β-Glycyrrhetinic acid using optimized lipid nanocapsules: A novel alternative treatment for Alzheimer's disease
SR Gad, RI El-Gogary, MY George… - International Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder and the most relevant form of
dementia affecting people worldwide. AD was reported to be associated with increased …
dementia affecting people worldwide. AD was reported to be associated with increased …
[HTML][HTML] Aspirin curcumin ester loaded biomimetic nanodrug improves cognitive deficits in a mouse model of Alzheimer's disease by regulating M1/M2 microglial …
Z Li, Z Song, C He, J Fan, W Yu, M Yang, P Li… - Materials Today …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disorder, tightly related
with microglia phenotypic polarization, which finally results in the stimulation of β-amyloid …
with microglia phenotypic polarization, which finally results in the stimulation of β-amyloid …
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