Lactobacilli dominance and vaginal pH: why is the human vaginal microbiome unique?

EA Miller, DAE Beasley, RR Dunn… - Frontiers in microbiology, 2016 - frontiersin.org
The human vaginal microbiome is dominated by bacteria from the genus Lactobacillus,
which create an acidic environment thought to protect women against sexually transmitted …

Towards a deeper understanding of the vaginal microbiota

M France, M Alizadeh, S Brown, B Ma, J Ravel - Nature microbiology, 2022 - nature.com
The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

[HTML][HTML] Cervicovaginal microbiota, women's health, and reproductive outcomes

SJ Kroon, J Ravel, WM Huston - Fertility and sterility, 2018 - Elsevier
The human microbiome project has shown a remarkable diversity of microbial ecology
within the human body. The vaginal microbiota is unique in that in many women it is most …

Host and microbiome interplay shapes the vaginal microenvironment

MS Kwon, HK Lee - Frontiers in immunology, 2022 - frontiersin.org
The female reproductive tract harbors a unique microbiome, especially the vagina. The
human vaginal microbiome exhibits a low diversity and is dominated by Lactobacillus …

Vaginal microbiome and its relationship to behavior, sexual health, and sexually transmitted diseases

FMT Lewis, KT Bernstein, SO Aral - Obstetrics & Gynecology, 2017 - journals.lww.com
The vaginal microbiota has great significance in maintaining vaginal health and protecting
the host from disease. Recent advances in molecular techniques and informatics allow …

Vaginal microbiome: normalcy vs dysbiosis

VS Saraf, SA Sheikh, A Ahmad, PM Gillevet… - Archives of …, 2021 - Springer
It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …

Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration

DE O'Hanlon, RA Come, TR Moench - BMC microbiology, 2019 - Springer
Background Lactic acid (protonated lactate) has broad antimicrobial activity. Vaginal
lactobacilli produce lactic acid, and are known to confer protection against reproductive tract …

Defence factors of vaginal lactobacilli

S Kovachev - Critical reviews in microbiology, 2018 - Taylor & Francis
Accurate knowledge of the composition and ecology of the vaginal microbial environment in
healthy women is necessary for understanding lactobacilli-dominated normal microbiota …

Microbial diversity in the vaginal microbiota and its link to pregnancy outcomes

A Baud, KH Hillion, C Plainvert, V Tessier, A Tazi… - Scientific reports, 2023 - nature.com
The vaginal microbiota refers to the microorganisms that reside in the vagina. These
microorganisms contribute significantly to a woman's reproductive and general health. A …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …