Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery

JW Moses, MB Leon, JJ Popma… - … England Journal of …, 2003 - Mass Medical Soc
Background Preliminary reports of studies involving simple coronary lesions indicate that a
sirolimus-eluting stent significantly reduces the risk of restenosis after percutaneous …

Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trial

G Weisz, MB Leon, DR Holmes, DJ Kereiakes… - Journal of the American …, 2006 - jacc.org
Objectives: The purpose of this study was to examine the two-year clinical outcomes in
patients enrolled in the Sirolimus-Eluting Stent in De Novo Native Coronary Lesions …

Five-year follow-up after sirolimus-eluting stent implantation: results of the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native Coronary Lesions) trial

G Weisz, MB Leon, DR Holmes, DJ Kereiakes… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this study was to examine the 5-year clinical safety and efficacy
outcomes in patients enrolled in the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native …

Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries

JJ Popma, MB Leon, JW Moses, DR Holmes Jr, N Cox… - Circulation, 2004 - Am Heart Assoc
Background—Sirolimus-eluting stents (SESs) reduce angiographic restenosis in patients
with focal, native coronary artery stenoses. This study evaluated the usefulness of SESs in …

Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial

D Ardissino, C Cavallini, E Bramucci, C Indolfi… - Jama, 2004 - jamanetwork.com
ContextPercutaneous coronary revascularization of small vessels is associated with a high
restenosis rate. Sirolimus-eluting stents reduce restenosis in simple and previously …

A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization

MC Morice, PW Serruys, JE Sousa… - … England Journal of …, 2002 - Mass Medical Soc
Background The need for repeated treatment of restenosis of a treated vessel remains the
main limitation of percutaneous coronary revascularization. Because sirolimus (rapamycin) …

Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment …

DJ Cohen, A Bakhai, C Shi, L Githiora, T Lavelle… - Circulation, 2004 - Am Heart Assoc
Background—Recently, sirolimus-eluting stents (SESs) have been shown to dramatically
reduce the risk of angiographic and clinical restenosis compared with bare metal stent …

Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial

J Fajadet, MC Morice, C Bode, P Barragan… - Circulation, 2005 - Am Heart Assoc
Background—The use of sirolimus-eluting coronary stents has been associated with a
nearly complete elimination of restenosis at 6 months and with a very low 1-year incidence …

Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary …

DR Holmes Jr, MB Leon, JW Moses, JJ Popma… - Circulation, 2004 - Am Heart Assoc
Background—This study evaluated a large group of patients enrolled in a double-blind
randomized trial of the sirolimus-eluting stent to document whether the initial clinical …

Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trial

MC Morice, PW Serruys, P Barragan, C Bode… - Journal of the American …, 2007 - jacc.org
Objectives: This study examined the clinical outcomes at 5 years in RAVEL (A Randomized
Comparison of a Sirolimus-Eluting Stent With a Standard Stent for Coronary …