The blood–brain barrier (BBB) restricts molecular and cellular trafficking between the blood
and the CNS. Although astrocytes are known to control BBB permeability, the molecular …

The blood–brain barrier (BBB), a critical guardian of communication between the periphery
and the brain, is frequently compromised in neurological diseases such as multiple sclerosis …

The blood–brain barrier (BBB) is a diffusion barrier, which impedes influx of most
compounds from blood to brain. Three cellular elements of the brain microvasculature …

Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

A wide range of central nervous system (CNS) disorders include neuroinflammatory events
that perturb blood–brain barrier (BBB) integrity. Mechanisms by which the BBB responds to …

abstract The blood-brain barrier (BBB) is a highly complex and dynamic barrier. It is formed
by an interdependent network of brain capillary endothelial cells, endowed with barrier …

More than 100 years ago, Ehlrich (1885) first described the existence of the blood-brain
barrier (BBB). The blood-brain barrier is an entity located between the blood and brain …

Impairments of the blood–brain barrier (BBB) and vascular dysfunction contribute to
Alzheimer's disease (AD) from the earliest stages. However, the influence of AD-affected …

The blood-brain barrier (BBB) is a physical and biochemical barrier that precisely controls
cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of …

Efficient neuronal signaling in the central nervous system strictly depends on a well‐
balanced microenvironment around glial cells, synapses, and axons. Unique features of the …