[HTML][HTML] Atopic dermatitis: an expanding therapeutic pipeline for a complex disease

T Bieber - Nature reviews Drug discovery, 2022 - nature.com
Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a complex
pathophysiology that underlies a wide spectrum of clinical phenotypes. AD remains …

[HTML][HTML] Innovation in atopic dermatitis: from pathogenesis to treatment

M Munera-Campos, JM Carrascosa - Actas Dermo-Sifiliográficas (English …, 2020 - Elsevier
Atopic dermatitis is the most common inflammatory skin disease and up to 20% of cases can
be classified as moderate to severe. Our understanding of the pathogenesis of this disease …

Impact of a decade of research into atopic dermatitis

PD Arkwright, JJ Koplin - The Journal of Allergy and Clinical Immunology …, 2023 - Elsevier
The last decade has seen an unprecedented pace of change, particularly of clinical
research in atopic dermatitis (AD). This review summarizes some key discoveries. Over the …

Efficacy of biologics in atopic dermatitis

J Wu, E Guttman-Yassky - Expert Opinion on Biological Therapy, 2020 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a heterogeneous disease. Recent advancements in
understanding AD pathogenesis resulted in the exponential expansion of its therapeutic …

The evolving landscape of biologic therapies for atopic dermatitis: Present and future perspective

E David, B Ungar, Y Renert‐Yuval… - Clinical & …, 2023 - Wiley Online Library
Atopic dermatitis (AD) is one of the most common, chronic inflammatory skin diseases with a
significant physical, emotional and socioeconomic burden. In recent years the …

[HTML][HTML] New and emerging systemic treatments for atopic dermatitis

M Newsom, AM Bashyam, EA Balogh, SR Feldman… - Drugs, 2020 - Springer
Atopic dermatitis (AD) is a prevalent inflammatory skin condition that, depending on its
severity, can cause enormous morbidity. Corticosteroids and systemic immunosuppression …

Understanding the immune landscape in atopic dermatitis: The era of biologics and emerging therapeutic approaches

M Moyle, F Cevikbas, JL Harden… - Experimental …, 2019 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, systemic, inflammatory disease that affects the skin and is
characterized by persistent itch and marked redness. AD is associated with an increased …

New pathogenic and therapeutic paradigms in atopic dermatitis

D Malajian, E Guttman-Yassky - Cytokine, 2015 - Elsevier
Atopic Dermatitis (AD) is a common inflammatory skin disease with increasing prevalence in
industrialized countries. Up to one-third of adults with AD have moderate-to-severe disease …

Therapeutic pipeline for atopic dermatitis: end of the drought?

AS Paller, K Kabashima, T Bieber - Journal of Allergy and Clinical …, 2017 - Elsevier
Until the past year, our therapeutic armamentarium for treating atopic dermatitis (AD) was
still primarily topical corticosteroids and, for more severe disease, systemic …

Advances in the pathophysiology of atopic dermatitis revealed by novel therapeutics and clinical trials

X Yang, N Kambe, R Takimoto-Ito… - Pharmacology & …, 2021 - Elsevier
Atopic dermatitis (AD) is an inflammatory skin disease arising from a complex interplay of
genetic, immune, and environmental factors. The development and successful marketing of …