The NOTCH signaling pathway plays an important role in regulating various biological
processes, including lineage specification and apoptosis. Multiple components of the …

Notch signaling is an evolutionary conserved pathway involved in intercellular signaling and
essential for proper cell fate choices during development. Thus, it could be involved in …

Background Mammalian early embryo development requires a well-orchestrated interplay of
cell signaling pathways. Notch is a major regulatory pathway involved in cell-fate …

The Notch signaling pathway is an evolutionarily conserved signaling system which has
been shown to be essential in cell fate specification and in numerous aspects of embryonic …

The formation of primordial follicles is a crucial process in the establishment of follicle pools
required for the female's reproductive life span. For laying hens, ample follicles are a …

During mammalian development, placental growth needs to be tightly controlled by
apoptosis. However, despite the potentially significant problems, the strategies used to …

Background Notch signaling is mainly regulated by Notch1 during development of chicken
germ stem cells; however, the molecular mechanisms that contribute to generation of these …

A critical process of early oogenesis is the entry of mitotic oogonia into meiosis, a cell cycle
switch regulated by a complex gene regulatory network. Although Notch pathway is involved …

The Notch signaling pathway is an evolutionarily conserved signaling mechanism and
mutations in its components disrupt cell fate specification and embryonic development in …

NOTCH signalling is an evolutionarily conserved pathway involved in intercellular
communication essential for cell fate choices during development. Although dispensable for …