ABSTRACT AR (androgen receptor) signaling is crucial for the development and
maintenance of the prostate as well as the initiation and progression of prostate cancer …

Purpose: Androgen receptor has a critical role in prostate cancer development and
progression. Cell death via autophagy may also contribute to prostate cancer progression …

Abstract Autophagy, or'self-eating', is an adaptive process that enables cells to cope with
metabolic, toxic, and even infectious stressors. Although the adaptive capability of …

Autophagy is a complex process involved in several cell activities, including tissue growth,
differentiation, metabolic modulation, and cancer development. In prostate cancer …

The role of autophagy is known to be highly complex and context-dependent, leading to
both cancer suppression and progression in several tumors including melanoma, breast and …

Autophagy is a complex process of autodigestion in conditions of cellular stress and it might
play an important role in the pathophysiology during carcinogenesis. We hypothesize that …

Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

Macro-autophagy is associated with drug resistance in various cancers and can function as
an adaptive response to maintain cell survival under metabolic stresses, including androgen …

Androgens regulate both the physiological development of the prostate and the pathology of
prostatic diseases. However, the mechanisms by which androgens exert their regulatory …

Simple Summary This paper is one in a series of articles that investigate the functional forms
of autophagy induced in tumor cells in response to various chemotherapeutic modalities …