Natural killer cells regulate diverse T cell responses

SQ Crome, PA Lang, KS Lang, PS Ohashi - Trends in immunology, 2013 - cell.com
Natural killer (NK) cells are important mediators of the immune response against microbial
pathogens and tumors. There is growing evidence from mouse and human studies that, NK …

NK cells regulating T cell responses: mechanisms and outcome

J Crouse, HC Xu, PA Lang, A Oxenius - Trends in immunology, 2015 - cell.com
Natural killer (NK) cells are important innate effectors in immunity. NK cells also have a role
in the regulation of the adaptive immune response, and have been shown, in different …

T cell regulation of natural killer cells

Y Kerdiles, S Ugolini, E Vivier - Journal of Experimental Medicine, 2013 - rupress.org
In light of their role in the immune response against tumors and viruses, natural killer (NK)
cells represent a promising target for immunotherapy. Before this target is reached, the …

Natural killer cells as an initial defense against pathogens

MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …

Regulation of natural killer cell activity

SE Kirwan, DN Burshtyn - Current opinion in immunology, 2007 - Elsevier
Information regarding the role of natural killer (NK) cells in the response to viruses,
intracellular bacteria and parasites continues to emerge. NK cells can directly lyse infected …

Functions of natural killer cells

E Vivier, E Tomasello, M Baratin, T Walzer… - Nature …, 2008 - nature.com
Natural killer (NK) cells are effector lymphocytes of the innate immune system that control
several types of tumors and microbial infections by limiting their spread and subsequent …

“Natural regulators”: NK cells as modulators of T cell immunity

IS Schuster, JD Coudert, CE Andoniou… - Frontiers in …, 2016 - frontiersin.org
Natural killer (NK) cells are known as frontline responders capable of rapidly mediating a
response upon encountering transformed or infected cells. Recent findings indicate that NK …

Natural killer cell biology: an update and future directions

KS Campbell, J Hasegawa - Journal of Allergy and Clinical Immunology, 2013 - Elsevier
Natural killer (NK) cells constitute a minor subset of normal lymphocytes that initiate innate
immune responses toward tumor and virus-infected cells. They can mediate spontaneous …

Targeting natural killer cells for improved immunity and control of the adaptive immune response

S Pierce, ES Geanes, T Bradley - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Natural killer (NK) cells are critical for targeting and killing tumor, virus-infected and stressed
cells as a member of the innate immune system. Recently, NK cells have also emerged as …

Signal transduction during activation and inhibition of natural killer cells

C Watzl, EO Long - Current protocols in immunology, 2010 - Wiley Online Library
Natural killer (NK) cells are important for early immune responses to viral infections and
cancer. Upon activation, NK cells secrete cytokines and chemokines, and kill sensitive target …