Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases

F Zahedipour, SA Hosseini, NC Henney… - Neural Regeneration …, 2022 - journals.lww.com
Inflammatory processes and proinflammatory cytokines have a key role in the cellular
processes of neurodegenerative diseases and are linked to the pathogenesis of functional …

Phytochemicals targeting nitric oxide signaling in neurodegenerative diseases

T Behl, T Rana, A Sehgal, HA Makeen, M Albratty… - Nitric oxide, 2023 - Elsevier
Neurodegenerative diseases are a set of diseases in which slow and progressive neuronal
loss occurs. Nitric oxide (NO) as a neurotransmitter performs key roles in the stimulation and …

[Retracted] Natural Products for Neurodegeneration: Regulating Neurotrophic Signals

MS Uddin, AA Mamun, MM Rahman… - Oxidative Medicine …, 2021 - Wiley Online Library
Neurodegenerative disorders (NDs) are heterogeneous groups of ailments typically
characterized by progressive damage of the nervous system. Several drugs are used to treat …

Neuroinflammation mechanisms and phytotherapeutic intervention: A systematic review

N Kaur, H Chugh, MK Sakharkar… - ACS chemical …, 2020 - ACS Publications
Neuroinflammation is indicated in the pathogenesis of several acute and chronic
neurological disorders. Acute lesions in the brain parenchyma induce intense and highly …

Alzheimer's disease: natural products as inhibitors of neuroinflammation

OA Olajide, SD Sarker - Inflammopharmacology, 2020 - Springer
Alzheimer's disease (AD) is the most common form of dementia and affects 44 million
people worldwide. New emerging evidence from pre-clinical and clinical investigations …

Phytochemicals against TNFα-Mediated Neuroinflammatory Diseases

L Subedi, SE Lee, S Madiha, BP Gaire, M Jin… - International journal of …, 2020 - mdpi.com
Tumor necrosis factor-alpha (TNF-α) is a well-known pro-inflammatory cytokine responsible
for the modulation of the immune system. TNF-α plays a critical role in almost every type of …

Targeting the TLR4 signaling pathway by polyphenols: a novel therapeutic strategy for neuroinflammation

M Rahimifard, F Maqbool, S Moeini-Nodeh… - Ageing research …, 2017 - Elsevier
A wide array of cell signaling mediators and their interactions play vital roles in
neuroinflammation associated with ischemia, brain trauma, developmental disorders and …

Therapeutic potential of different natural products for the treatment of Alzheimer's Disease

B Chakraborty, N Mukerjee, S Maitra… - Oxidative Medicine …, 2022 - Wiley Online Library
A high incidence of dementia (60–80%) and a high rate of memory loss are two of the most
common symptoms of Alzheimer's disease (AD), which affects the elderly. Researchers have …

The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer's disease: a narrative review

Q Zhang, Y Yan - Neural Regeneration Research, 2023 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older
adult people and is characterized by memory loss, progressive cognitive impairment, and …

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

C Spagnuolo, S Moccia, GL Russo - European journal of medicinal …, 2018 - Elsevier
Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …