Elevated levels of plasma free fatty acids (FFA), which are commonly found in obesity,
induce insulin resistance. FFA activate protein kinases including the proinflammatory IκBα …

Resveratrol is a naturally occurring polyphenol found in many dietary sources and red wine.
Recognized as a cancer chemoprevention agent, an anti-inflammatory factor and an …

Studies in animal models of diabetes and obesity have shown that resveratrol mitigates
complications of metabolic diseases, beyond those resulting from oxidative stress …

We performed the largest randomized, placebo‐controlled clinical trial to date (N= 112, 12‐
week intervention) to investigate the effects and safety of resveratrol supplementation on …

Insulin resistance, the hallmark of type 2 diabetes mellitus (T2DM), is linked to
hyperinsulinemia, which develops to counterbalance initial peripheral hormone resistance …

Background: Resveratrol is a polyphenol chemical that naturally occurs in many plant-based
dietary products, most notably, red wine. Discovered in 1939, widespread interest in the …

The polyphenol compound resveratrol (RSV) has attracted attention due to its reputed
beneficial effects on insulin sensitivity. Our lab has previously identified protective effects of …

Resveratrol has been reported to improve metabolic function in metabolically abnormal
rodents and humans, but it has not been studied in nonobese people with normal glucose …

Higher levels of body fat are associated with increased risk for development of numerous
adverse health conditions. Phytochemicals are potential agents to inhibit differentiation of …

The peroxisome proliferator–activated receptor (PPAR) γ is essential for the formation and
function of adipocytes. It is also involved in regulating insulin sensitivity and is the functional …