[HTML][HTML] Mitochondria as potential targets in Alzheimer disease therapy: an update
G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …
affects mostly the elderly population. At the moment, no effective treatments are available in …
Mitochondrial biology in Alzheimer's disease pathogenesis
J. Neurochem.(2010) 114, 933–945. Abstract Despite the increasing knowledge of
Alzheimer's disease (AD) management with novel pharmacologic agents, most of them are …
Alzheimer's disease (AD) management with novel pharmacologic agents, most of them are …
[HTML][HTML] Targeting mitochondria in Alzheimer disease: rationale and perspectives
A decline in mitochondrial function plays a key role in the aging process and increases the
incidence of age-related disorders, including Alzheimer disease (AD). Mitochondria—the …
incidence of age-related disorders, including Alzheimer disease (AD). Mitochondria—the …
Mitochondrial dysfunction: different routes to Alzheimer's disease therapy
Mitochondria are dynamic ATP‐generating organelle which contribute to many cellular
functions including bioenergetics processes, intracellular calcium regulation, alteration of …
functions including bioenergetics processes, intracellular calcium regulation, alteration of …
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: Recent advances
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
The role of mitochondrial dysfunction in Alzheimer's disease: A potential pathway to treatment
AB Reiss, S Ahmed, C Dayaramani, AD Glass… - Experimental …, 2022 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …
is characterized by progressive memory loss and cognitive impairment. Our understanding …
Mitochondrial therapeutic interventions in Alzheimer's disease
Alzheimer's Disease (AD) is one of the most common age-related neurodegenerative
diseases in the developed world. Treatment of AD is particularly challenging as the drug …
diseases in the developed world. Treatment of AD is particularly challenging as the drug …
[HTML][HTML] Mitochondrial dysfunction: a potential therapeutic target to treat Alzheimer's disease
Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …
[HTML][HTML] Mitochondrial dysfunction in Alzheimer's disease: opportunities for drug development
Alzheimer's disease (AD) is one of the major reasons for 60-80% cases of senile dementia
occurring as a result of the accumulation of plaques and tangles in the hippocampal and …
occurring as a result of the accumulation of plaques and tangles in the hippocampal and …
Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities
JM Perez Ortiz, RH Swerdlow - British journal of pharmacology, 2019 - Wiley Online Library
Dysfunction of cell bioenergetics is a common feature of neurodegenerative diseases, the
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …