Drug resistance is a hot topic issue in cancer research and therapy. Although cancer therapy
including radiotherapy and anti‐cancer drugs can kill malignant cells within the tumor …

Triptolide is a compound extracted from the Chinese herb Tripterygium wilfordii Hook. f.
Triptolide has potent anticancer activity. However, the mechanisms by which triptolide exerts …

The need for naturally occurring constituents is driven by the rise in the cancer prevalence
and the unpleasant side effects associated with chemotherapeutics. Triptolide, the primary …

Triptolide is known to be involved in many cellular events, such as those related to
immunosuppressive and antitumor activity. We investigated whether triptolide mediates …

Triptolide (PG490), a diterpene triepoxide, is a potent immunosuppressive agent extracted
from the Chinese herbTripterygium wilfordii. We have previously shown that triptolide blocks …

Triptolide, derived from the traditional Chinese herb, Tripterygium wilfordii, sensitizes cancer
cells to apoptosis. Glioblastoma multiforme (GBM), which accounts for most cases of central …

The present study investigated the effect of triptolide on viability and apoptosis along with
underlying mechanism in liver cancer cells. CCK-8 assay showed that triptolide treatment for …

Triptolide (TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies
indicated that TPL inhibits cell proliferation, induces cell apoptosis, inhibits tumor metastasis …

Cisplatin is an anticancer agent that is effective against several types of cancer, including
gastric cancer. However, its therapeutic application is limited by its toxicity in normal tissues …

Triptolide, a traditional Chinese medicine, has been reported to be effective in the treatment
of auto-immune diseases, and it can also induce anti-neoplastic activity on several human …