Potential statin drug interactions in elderly patients: a review

I Damiani, A Corsini, S Bellosta - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Persons aged more than 65 years may be more prone to suffer from chronic
diseases and comorbidities (as demonstrated by the recent COVID-19 pandemics) and are …

Prevalence of statin-drug interactions in older people: a systematic review

M Thai, E Reeve, SN Hilmer, K Qi, SA Pearson… - European journal of …, 2016 - Springer
Purpose Statins are among the most frequently prescribed medications internationally. Older
people are commonly prescribed multiple medications and are at an increased risk of drug …

Statins and their interactions with other lipid-modifying medications: safety issues in the elderly

CKM Ho, SW Walker - Therapeutic advances in drug safety, 2012 - journals.sagepub.com
Inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase,
commonly known as statins, are widely used in both primary and secondary prevention of …

Age-related differences in the prevalence of potential drug-drug interactions in ambulatory dyslipidaemic patients treated with statins

SS Egger, AER Bravo, L Hess, RG Schlienger… - Drugs & aging, 2007 - Springer
Background and objective Elderly patients may be at higher risk of drug-drug interactions
(DDIs) because of polypharmacy. This study evaluated age-specific differences in the …

Statin drug interactions and related adverse reactions: an update

S Bellosta, A Corsini - Expert opinion on drug safety, 2018 - Taylor & Francis
Introduction: Statins reduce the risk of cardiovascular morbidity and mortality in patients with
or at risk for cardiovascular disease and their use is expanding, especially in elderly. Statins …

Prevalence of potential and clinically relevant statin–drug interactions in frail and robust older inpatients

M Thai, S Hilmer, SA Pearson, E Reeve, D Gnjidic - Drugs & aging, 2015 - Springer
Background A significant proportion of older people are prescribed statins and are also
exposed to polypharmacy, placing them at increased risk of statin–drug interactions …

Implications of statin adverse effects in the elderly

BA Golomb - Expert opinion on drug safety, 2005 - Taylor & Francis
The elderly differ from younger people in the relation of cholesterol to heart disease and
mortality. Clinical trial evidence supports epidemiological findings in showing that high …

[PDF][PDF] Statins and the elderly: recent evidence and current indications

GG Schiattarella, C Perrino, F Magliulo, F Ilardi… - Aging Clin Exp …, 2012 - researchgate.net
Cardiovascular disease (CVD) is estimated to remain as the main cause of death in
developed nations over the next 30 years, with increased prevalence in the older …

Statin prescribing in the elderly: special considerations

M Leya, NJ Stone - Current Atherosclerosis Reports, 2017 - Springer
Abstract Purpose of Review Our aim was to examine the current evidence behind
prescribing statins to individuals over 65 years of age with emphasis on those older than 75 …

[HTML][HTML] Statins for primary cardiovascular prevention in the elderly

J Pedro-Botet, E Climent, JJ Chillarón… - Journal of geriatric …, 2015 - ncbi.nlm.nih.gov
The elderly population is increasing worldwide, with subjects> 65 years of age constituting
the fastest-growing age group. Furthermore, the elderly face the greatest risk and burden of …