Applying design of experiments (DoE) on the properties of buccal film for nicotine delivery

J Suksaeree, B Chaichawawut, M Srichan… - e-Polymers, 2021 - degruyter.com
Abstract Design of experiments is used to optimize ratios between deproteinized natural
rubber latex, Eudragit® NM 30 D, and pectin for nicotine buccal film with dependent …

Formulation and characterization of nicotine thin films for smoking cessation through buccal delivery

M Konda, KM Chinnala, L Samineni… - Research Journal of …, 2016 - indianjournals.com
Buccal films are the promising technology with fast onset of activity. The current research
was intended to prepare buccal thin films of nicotine to augment bioavailability and evade …

Formulation design of oral strip-films based on PVA/PVP polymer blends for nicotine delivery

W Pichayakorn, P Maneewattanapinyo… - Journal of Polymers and …, 2022 - Springer
This work prepared oral strip-film for nicotine delivery using polyvinyl alcohol and
polyvinylpyrrolidone as polymeric film and glycerin as a plasticizer. The formulas were …

Development and in vitro/in vivo evaluations of bioadhesive buccal tablets for nicotine replacement therapy

G Ikinci, S Şenel, L Tokgözoğlu… - Die Pharmazie-An …, 2006 - ingentaconnect.com
Buccal bioadhesive tablet formulations of nicotine hydrogen tartrate (NHT) for nicotine
replacement therapy (NRT) were developed using chitosan and carbomer at different ratios …

A novel tri-layered buccal mucoadhesive patch for drug delivery: assessment of nicotine delivery

S Rao, Y Song, F Peddie… - Journal of Pharmacy and …, 2011 - academic.oup.com
Objectives The aim of this study was to assess the potential of a novel delivery device for
administering drugs that suffer from a high degree of first-pass metabolism. Methods A tri …

Acrylic matrix type nicotine transdermal patches: in vitro evaluations and batch-to-batch uniformity

T Pongjanyakul, S Prakongpan… - Drug development and …, 2003 - Taylor & Francis
Nicotine transdermal patches (NTPs) were fabricated using an acrylic pressure sensitive
adhesive emulsion to form a transparent matrix film. An automated thin layer …

Optimization of two biopolymer-based oral films for the delivery of bioactive molecules

PM Castro, P Fonte, A Oliveira, AR Madureira… - Materials Science and …, 2017 - Elsevier
An experimental design was established in order to optimize the mechanical properties of
two oral film formulations intended for oral delivery of bioactive compounds …

[PDF][PDF] Formula optimization and in vitro release kinetic studies of diltiazem hydrochloride mucoadhesive bilayer buccal film

L Winarti, AZ Laily, L Sari, ED Irawan… - International Journal of …, 2021 - academia.edu
Objective: This research aims to determine the amount of hydroxypropyl methylcellulose
(HPMC) and chitosan, which can produce the optimum buccal film formula and to determine …

Quality by Design-Guided Systematic Development and Optimization of Mucoadhesive Buccal Films

AAA Hassan, K Kristó, YHEY Ibrahim, G Regdon Jr… - Pharmaceutics, 2023 - mdpi.com
Mucoadhesive buccal films have found increased popularity in pharmaceutical drug delivery
due to the several advantages that they possess. The present study strives to develop and …

Development of transdermal system containing nicotine by using sustained release dosage design

F Tirnaksiz, Z Yuce - Il Farmaco, 2005 - Elsevier
This study was carried out to develop a membrane-controlled transdermal formulation (TF)
of nicotine by using sustained release dosage design (SRDD). TFs were prepared with …