Molecular mechanisms and potential therapeutical targets in Huntington's disease
C Zuccato, M Valenza, E Cattaneo - Physiological reviews, 2010 - journals.physiology.org
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat
expansion in the gene encoding for huntingtin protein. A lot has been learned about this …
expansion in the gene encoding for huntingtin protein. A lot has been learned about this …
Huntington's disease: mechanisms of pathogenesis and therapeutic strategies
M Jimenez-Sanchez, F Licitra… - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Huntington's disease is a late-onset neurodegenerative disease caused by a CAG
trinucleotide repeat in the gene encoding the huntingtin protein. Despite its well-defined …
trinucleotide repeat in the gene encoding the huntingtin protein. Despite its well-defined …
Loss of normal huntingtin function: new developments in Huntington's disease research
E Cattaneo, D Rigamonti, D Goffredo, C Zuccato… - Trends in …, 2001 - cell.com
Huntington's disease is characterized by a loss of brain striatal neurons that occurs as a
consequence of an expansion of a CAG repeat in the huntingtin protein. The resulting …
consequence of an expansion of a CAG repeat in the huntingtin protein. The resulting …
Huntington's disease: seeing the pathogenic process through a genetic lens
JF Gusella, ME MacDonald - Trends in biochemical sciences, 2006 - cell.com
Thirteen years ago, the culmination of genetic rather than biochemical strategies resulted in
the identification of the root cause of Huntington's disease: an expanded CAG trinucleotide …
the identification of the root cause of Huntington's disease: an expanded CAG trinucleotide …
Huntington's disease: from pathology and genetics to potential therapies
S Imarisio, J Carmichael, V Korolchuk… - Biochemical …, 2008 - portlandpress.com
Huntington's disease (HD) is a devastating autosomal dominant neurodegenerative disease
caused by a CAG trinucleotide repeat expansion encoding an abnormally long …
caused by a CAG trinucleotide repeat expansion encoding an abnormally long …
Genetics and neuropathology of Huntington's disease
A Reiner, I Dragatsis, P Dietrich - International review of neurobiology, 2011 - Elsevier
Huntington's disease (HD) is an autosomal dominant progressive neurodegenerative
disorder that prominently affects the basal ganglia, leading to affective, cognitive, behavioral …
disorder that prominently affects the basal ganglia, leading to affective, cognitive, behavioral …
Recent advances in understanding the pathogenesis of Huntington's disease
PH Reddy, M Williams, DA Tagle - Trends in neurosciences, 1999 - cell.com
Huntington's disease (HD) is an autosomal, dominantly inherited neurodegenerative
disorder that is characterized by abnormal involuntary movements (chorea), intellectual …
disorder that is characterized by abnormal involuntary movements (chorea), intellectual …
[HTML][HTML] The biological function of the Huntingtin protein and its relevance to Huntington's Disease pathology
J Schulte, JT Littleton - Current trends in neurology, 2011 - ncbi.nlm.nih.gov
Huntington's Disease is an adult-onset dominant heritable disorder characterized by
progressive psychiatric disruption, cognitive deficits, and loss of motor coordination. It is …
progressive psychiatric disruption, cognitive deficits, and loss of motor coordination. It is …
Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies
M Borrell-Pages, D Zala, S Humbert… - Cellular and Molecular Life …, 2006 - Springer
Huntington's disease (HD) is a neurodegenerative disorder that usually starts in middle age
and is characterized by involuntary movements (chorea), personality changes and …
and is characterized by involuntary movements (chorea), personality changes and …
The molecular biology of Huntington's disease
LW Ho, J Carmichael, J Swartz, A Wyttenbach… - Psychological …, 2001 - cambridge.org
Background. Huntington's disease (HD) is a fatal neurodegenerative disorder with an
autosomal dominant mode of inheritance. It leads to progressive dementia, psychiatric …
autosomal dominant mode of inheritance. It leads to progressive dementia, psychiatric …
相关搜索
- huntington's disease therapeutic strategies
- huntington's disease molecular mechanisms
- therapeutic strategies mechanisms of pathogenesis
- huntington's disease cag repeat
- huntington's disease pathogenic process
- huntington's disease genetics and neuropathology
- huntington's disease mechanisms of pathogenesis
- huntington's disease molecular biology
- huntington's disease huntingtin function
- huntington's disease genetic lens
- huntington's disease pathology and genetics