Celastrol, a natural bioactive ingredient derived from Tripterygium wilfordii Hook F, exhibits
significant broad-spectrum anticancer activities for the treatment of a variety of cancers …

Cancer is one of the world's biggest healthcare burdens and despite the current
advancements made in treatment plans, the outcomes for oncology patients have yet to …

Celastrol is a pentacyclic triterpenoid extracted from the traditional Chinese medicine
Tripterygium wilfordii Hook F., which has multiple pharmacological activities. In particular …

Celastrol, a principal bioactive ingredient of Tripterygium wilfordii Hook F, has gained
extensive exploration due to its unique structure features and multiple promising biological …

Celastrol, a quinone‐methide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …

Despite the advancement in the well-equipped and sophisticated laboratories and facilities,
cancer remains to be a major cause of death worldwide. Consequently, further investigation …

Celastrol, a pentacyclic triterpene extracted from the roots of Tripterygium Wilfordi (thunder
god vine) plant, has shown promising antitumor activities in various preclinical studies …

Celastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium
wilfordii Hook F (TWHF). In 2007, the 'Cell'journal ranked celastrol, triptolide, artemisinin …

Understanding the molecular basis and target of traditional medicine is critical for drug
development. Celastrol, derived from Trypterygium wilfordii Hook F.(“Thunder of God Vine”) …

In the recent years, much attention has been focused on identifying bioactive compounds
from medicinal plants that could be employed in therapeutics, which is attributed to their …