The roles of tertiary lymphoid structures in chronic diseases
Y Sato, K Silina, M van den Broek, K Hirahara… - Nature Reviews …, 2023 - nature.com
Tertiary lymphoid structures (TLSs) are ectopic lymphoid tissues that drive antigen-specific
immune responses at sites of chronic inflammation. Unlike secondary lymphoid organs such …
immune responses at sites of chronic inflammation. Unlike secondary lymphoid organs such …
[HTML][HTML] Developmental stages of tertiary lymphoid tissue reflect local injury and inflammation in mouse and human kidneys
Tertiary lymphoid tissues (TLTs) are inducible ectopic lymphoid tissues in chronic
inflammatory states and function as sites of priming local immune responses. We previously …
inflammatory states and function as sites of priming local immune responses. We previously …
The lymphatics in kidney health and disease
MD Donnan, Y Kenig-Kozlovsky… - Nature Reviews …, 2021 - nature.com
The mammalian vascular system consists of two networks: the blood vascular system and
the lymphatic vascular system. Throughout the body, the lymphatic system contributes to …
the lymphatic vascular system. Throughout the body, the lymphatic system contributes to …
[HTML][HTML] Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis
Kidney involvement confers significant morbidity and mortality in patients with systemic
lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse …
lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse …
Understanding immune cells in tertiary lymphoid organ development: it is all starting to come together
GW Jones, DG Hill, SA Jones - Frontiers in immunology, 2016 - frontiersin.org
Tertiary lymphoid organs (TLOs) are frequently observed in tissues affected by non-
resolving inflammation as a result of infection, autoimmunity, cancer, and allograft rejection …
resolving inflammation as a result of infection, autoimmunity, cancer, and allograft rejection …
Tertiary lymphoid structures: autoimmunity goes local
E Pipi, S Nayar, DH Gardner, S Colafrancesco… - Frontiers in …, 2018 - frontiersin.org
Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune
diseases. TLS present features of secondary lymphoid organs such as segregated T and B …
diseases. TLS present features of secondary lymphoid organs such as segregated T and B …
Tertiary lymphoid structures are critical for cancer prognosis and therapeutic response
Q Zhang, S Wu - Frontiers in Immunology, 2023 - frontiersin.org
Tertiary lymphoid structures (TLSs) are ectopic lymphocyte aggregates that form at sites of
chronic inflammation, including cancers, in non-lymphoid tissues. Although the formation of …
chronic inflammation, including cancers, in non-lymphoid tissues. Although the formation of …
Tertiary lymphoid structures in cancer and beyond
Tertiary lymphoid structures (TLS) are ectopic lymphoid formations found in inflamed,
infected, or tumoral tissues. They exhibit all the characteristics of structures in the lymph …
infected, or tumoral tissues. They exhibit all the characteristics of structures in the lymph …
Tertiary lymphoid structures and cytokines interconnections: the implication in cancer immunotherapy
H Li, JY Ding, MJ Zhang, HJ Yu, ZJ Sun - Cancer Letters, 2023 - Elsevier
Tertiary lymphoid structures (TLSs) are organized aggregates of lymphocytes and antigen-
presenting cells that develop in non-lymphoid tissues during chronic inflammation …
presenting cells that develop in non-lymphoid tissues during chronic inflammation …
[HTML][HTML] Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney
Y Sato, A Mii, Y Hamazaki, H Fujita, H Nakata… - JCI insight, 2016 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a common clinical condition defined as a rapid decline in kidney
function. AKI is a global health burden, estimated to cause 2 million deaths annually …
function. AKI is a global health burden, estimated to cause 2 million deaths annually …