Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas …
Recent research indicates that the post-transcriptional regulator Crc modulates susceptibility
to antibiotics and virulence in Pseudomonas aeruginosa. Several P. aeruginosa virulence …
to antibiotics and virulence in Pseudomonas aeruginosa. Several P. aeruginosa virulence …
The global regulator Crc plays a multifaceted role in modulation of type III secretion system in Pseudomonas aeruginosa
The opportunistic pathogen P seudomonas aeruginosa utilizes type III secretion system (T 3
SS) to translocate effector proteins into eukaryotic host cells that subvert normal host cell …
SS) to translocate effector proteins into eukaryotic host cells that subvert normal host cell …
[HTML][HTML] Transcriptome profiling reveals links between ParS/ParR, MexEF-OprN, and quorum sensing in the regulation of adaptation and virulence in Pseudomonas …
Abstract Background The ParS/ParR two component regulatory system plays critical roles for
multidrug resistance in Pseudomonas aeruginosa. It was demonstrated that in the presence …
multidrug resistance in Pseudomonas aeruginosa. It was demonstrated that in the presence …
[HTML][HTML] Virulence and Metabolism Crosstalk: Impaired Activity of the Type Three Secretion System (T3SS) in a Pseudomonas aeruginosa Crc-Defective Mutant
T Gil-Gil, T Cuesta, S Hernando-Amado… - International Journal of …, 2023 - mdpi.com
Pseudomonas aeruginosa is a ubiquitous nosocomial opportunistic pathogen that harbors
many virulence determinants. Part of P. aeruginosa success colonizing a variety of habitats …
many virulence determinants. Part of P. aeruginosa success colonizing a variety of habitats …
[HTML][HTML] Identification of Small Molecules Blocking the Pseudomonas aeruginosa Type III Secretion System Protein PcrV
C Sundin, M Saleeb, S Spjut, L Qin, M Elofsson - Biomolecules, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic bacterial pathogen that employs its type III
secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the …
secretion system (T3SS) during the acute phase of infection to translocate cytotoxins into the …
The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa
The capacity of a bacterial pathogen to produce a disease in a treated host depends on the
former's virulence and resistance to antibiotics. Several scattered pieces of evidence …
former's virulence and resistance to antibiotics. Several scattered pieces of evidence …
[HTML][HTML] Type III Secretion Protein, PcrV, Impairs Pseudomonas aeruginosa Biofilm Formation by Increasing M1 Macrophage-Mediated Anti-bacterial Activities
H Yu, J Xiong, J Qiu, X He, H Sheng, Q Dai… - Frontiers in …, 2020 - frontiersin.org
Pseudomonas aeruginosa biofilms employ a variety of strategies to hijack the host immune
defense system to achieve chronic infection. However, the bacterial components that are …
defense system to achieve chronic infection. However, the bacterial components that are …
[HTML][HTML] Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa
J Zhao, X Yu, M Zhu, H Kang, J Ma, M Wu, J Gan… - PLoS …, 2016 - journals.plos.org
Although quorum-sensing (QS) systems are important regulators of virulence gene
expression in the opportunistic human pathogen Pseudomonas aeruginosa, their detailed …
expression in the opportunistic human pathogen Pseudomonas aeruginosa, their detailed …
[HTML][HTML] Tobramycin reduces key virulence determinants in the proteome of Pseudomonas aeruginosa outer membrane vesicles
Tobramycin is commonly used to treat Pseudomonas aeruginosa lung infections in patients
with Cystic Fibrosis (CF). Tobramycin treatment leads to increased lung function and fewer …
with Cystic Fibrosis (CF). Tobramycin treatment leads to increased lung function and fewer …
[HTML][HTML] The Transcriptional Regulator CzcR Modulates Antibiotic Resistance and Quorum Sensing in Pseudomonas aeruginosa
G Dieppois, V Ducret, O Caille, K Perron - PloS one, 2012 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa responds to zinc, cadmium and
cobalt by way of the CzcRS two-component system. In presence of these metals the …
cobalt by way of the CzcRS two-component system. In presence of these metals the …
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