Multi‐targeted therapy by curcumin: how spicy is it?

A Goel, S Jhurani, BB Aggarwal - Molecular Nutrition & Food …, 2008 - Wiley Online Library
Although traditional medicines have been used for thousands of years, for most such
medicines neither the active component nor their molecular targets have been very well …

Anticancer activity of curcumin and its analogues: preclinical and clinical studies

A Allegra, V Innao, S Russo, D Gerace… - Cancer …, 2017 - Taylor & Francis
Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …

Molecular targets of curcumin for cancer therapy: an updated review

PD Kasi, R Tamilselvam, K Skalicka-Woźniak… - Tumor Biology, 2016 - Springer
In recent years, natural edible products have been found to be important therapeutic agents
for the treatment of chronic human diseases including cancer, cardiovascular disease, and …

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials

AS Strimpakos, RA Sharma - Antioxidants & redox signaling, 2008 - liebertpub.com
Curcumin is a natural polyphenol used in ancient Asian medicine. Since the first article
referring to the use of curcumin to treat human disease was published in The Lancet in …

Curcumin―the paradigm of a multi-target natural compound with applications in cancer prevention and treatment

MH Teiten, S Eifes, M Dicato, M Diederich - Toxins, 2010 - mdpi.com
As cancer is a multifactor disease, it may require treatment with compounds able to target
multiple intracellular components. We summarize here how curcumin is able to modulate …

The targets of curcumin

H Zhou, CS Beevers, S Huang - Current drug targets, 2011 - ingentaconnect.com
Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

Is curcumin the answer to future chemotherapy cocktail?

WY Kong, SC Ngai, BH Goh, LH Lee, TT Htar… - Molecules, 2021 - mdpi.com
The rise in cancer cases in recent years is an alarming situation worldwide. Despite the
tremendous research and invention of new cancer therapies, the clinical outcomes are not …

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

J Epstein, IR Sanderson, TT MacDonald - British journal of nutrition, 2010 - cambridge.org
Curcumin is the active ingredient of turmeric. It is widely used as a kitchen spice and food
colorant throughout India, Asia and the Western world. Curcumin is a major constituent of …

[HTML][HTML] Cancer-linked targets modulated by curcumin

N Hasima, BB Aggarwal - International journal of biochemistry and …, 2012 - ncbi.nlm.nih.gov
In spite of major advances in oncology, the World Health Organization predicts that cancer
incidence will double within the next two decades. Although it is well understood that cancer …

Curcumin, a component of golden spice: from bedside to bench and back

S Prasad, SC Gupta, AK Tyagi, BB Aggarwal - Biotechnology advances, 2014 - Elsevier
Although the history of the golden spice turmeric (Curcuma longa) goes back thousands of
years, it is only within the past century that we learned about the chemistry of its active …