[HTML][HTML] HNMT upregulation induces cancer stem cell formation and confers protection against oxidative stress through interaction with HER2 in non-small-cell lung …

KT Kuo, CH Lin, CH Wang, NW Pikatan… - International journal of …, 2022 - mdpi.com
Background: The treatment of non-small-cell lung cancer (NSCLC) involves platinum-based
chemotherapy. It is typically accompanied by chemoresistance resulting from antioxidant …

Overexpression of miR-758 inhibited proliferation, migration, invasion, and promoted apoptosis of non-small cell lung cancer cells by negatively regulating HMGB

GH Zhou, YY Lu, JL Xie, ZK Gao, XB Wu… - Bioscience …, 2019 - portlandpress.com
Non-small cell lung cancer (NSCLC) is one of the most fatal types of cancer with significant
mortality and morbidity worldwide. MicroRNAs (miRs) have been confirmed to have positive …

[HTML][HTML] Activation of histamine H4 receptors decreases epithelial-to-mesenchymal transition progress by inhibiting transforming growth factor-β1 signalling pathway in …

WK Cai, J Hu, T Li, JR Meng, X Ma, SJ Yin… - European journal of …, 2014 - Elsevier
Previous investigations found that epithelial-to-mesenchymal transition (EMT) was an
important character of non-small cell lung cancer (NSCLC) and it was also suggested that …

miR-152/TNS1 axis inhibits non-small cell lung cancer progression through Akt/mTOR/RhoA pathway

J Duan, L Wang, L Shang, S Yang, H Wu… - Bioscience …, 2021 - portlandpress.com
Aim: The purpose of the present study was to explore the function and mechanism of tensin
1 (TNS1) in non-small cell lung cancer (NSCLC) progression. Methods: The expression of …

[HTML][HTML] Methyltransferase-like 3 upregulation is involved in the chemoresistance of non-small cell lung cancer

L Shi, Y Gong, L Zhuo, S Wang, S Chen… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Treatments for non-small cell lung cancer (NSCLC) have improved
tremendously, but therapeutic resistance is a common and major clinical challenge in …

Nm23-H1 inhibits hypoxia induced epithelial-mesenchymal transition and stemness in non-small cell lung cancer cells

C Wu, Y Zhuang, J Zhou, S Liu, X Zou, J Wu… - Biological …, 2019 - degruyter.com
The Nm23 gene has been acknowledged to play a crucial role in lung cancer metastasis
inhibitory cascades controlled by multiple factors. Low expression or allelic deletion of nm23 …

LINC00680 promotes the progression of non-small cell lung cancer and functions as a sponge of miR-410-3p to enhance HMGB1 expression

H Wang, L Feng, Y Zheng, W Li, L Liu, S Xie… - OncoTargets and …, 2020 - Taylor & Francis
Purpose LINC00680 was reported to be involved in various cancers through multiple
mechanisms. Therefore, we intended to investigate its role in the progression of non-small …

Effects of microRNA‐513b on cell proliferation, apoptosis, invasion, and migration by targeting HMGB3 through regulation of mTOR signaling pathway in non‐small …

J Wang, Z Sheng, Y Cai - Journal of Cellular Physiology, 2019 - Wiley Online Library
This study aimed to explore the underlying mechanism of miR‐513b and HMGB3 in
regulating non‐small‐cell lung cancer (NSCLC). NSCLC tumor, adjacent tissues, and cell …

[HTML][HTML] HAMP predicts a pivotal role in modulating the malignant behaviors of non-small cell lung cancer cells

Z Li, J Liu, P Wang, B Zhang, G He, L Yang - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Hepcidin antimicrobial peptide (HAMP) is a small peptide hormone recognized
for its role in iron metabolism and cancer treatment. The purpose of this study was to …

An antioxidant feedforward cycle coordinated by linker histone variant H1. 2 and NRF2 that drives nonsmall cell lung cancer progression

Y Chen, J Shi, X Wang, L Zhou… - Proceedings of the …, 2023 - National Acad Sciences
Nonsmall cell lung cancer (NSCLC) is highly malignant with limited treatment options,
platinum-based chemotherapy is a standard treatment for NSCLC with resistance commonly …