Both drug delivery performance and various age-related physical, mental and physiological
changes can affect drug effectiveness and safety in elderly patients. The many drug delivery …

The number of older people globally is increasing, contributing to a growing burden of
morbidity and mortality. With this shift in population demographic, comes a new challenge in …

Older adults with multimorbidity, polypharmacy, and complex health needs are the major
consumer of health care. Ensuring that medicines are used safely, effectively, and delivered …

Generally, we like to see ageing as a process that is happening to people older than
ourselves. However the process of ageing impacts on a wide range of functions within the …

Ageing is associated with several changes in human organs, which result in altered
medication pharmacokinetics and pharmacodynamics. Ageing is also associated with …

Demographic evolution will considerably increase the number of people aged 65 years and
beyond in the coming decades. The elderly not only represent the most heterogeneous …

Across the globe over the last few decades, there has been a remarkable increase in the
proportion of the population which is elderly, and this trend is set to continue. Data from 10 …

BACKGROUND:: Physiologic changes and disease-related alterations in organ function
occur with aging. These changes can affect drug pharmacokinetics in older persons …

Age-adapted drug formulations are a challenge in drug development. This paper describes
the special requirements of paediatric and geriatric patients, and new ideas to solve the …

Older adults are the main users of medicine and due to their multimorbidity are often
faced/confronted with a complex medication management. This review article provides a …