Investigation of neurodegeneration in glaucoma, a leading cause of irreversible blindness
worldwide, has been obfuscated by the lack of an efficient model that provides chronic, mild …

A reliable animal model providing chronic and persistent ocular hypertension and
characteristic neurodegeneration is essential to recapitulate human glaucoma and …

Background: Glaucoma is an irreversible and blinding neurodegenerative disease that is
characterized by progressive loss of retinal ganglion cells. The current animal models of …

Glaucoma is an optic neuropathy commonly associated with elevated intraocular pressure
(IOP) resulting in progressive loss of retinal ganglion cells (RGCs) and optic nerve …

Glaucoma is one of the leading causes of loss of vision. The problems associated with the
marketed formulations of anti-glaucoma drugs are low bioavailability, unwanted side effects …

The human eye's intricate anatomical and physiological design necessitates tailored
approaches for managing ocular diseases. Recent advancements in ophthalmology …

Hydrogels, as crosslinked polymeric three dimensional networks, possess unique structure
and behavior in response to the internal and/or external stimuli. As a result, they offer great …

Glaucoma is extensively treated with topical eye drops containing drugs. However, the
retention time of the loaded drugs and the in vivo bioavailability of the drugs are highly …

Glaucoma is an irreversible and blinding neurodegenerative disease of the eye, and is
characterized by progressive loss of retinal ganglion cells (RGCs). Since endogenous …

Objectives Ocular hypertension is a primary risk factor for glaucoma and results in retinal
ganglion cell (RGC) degeneration. Current animal models of glaucoma lack severe RGC …