Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances …

GR Gandhi, G Jothi, PJ Antony, K Balakrishna… - European journal of …, 2014 - Elsevier
In this study, the therapeutic efficacy of gallic acid from Cyamopsis tetragonoloba (L.)
Taub.(Fabaceae) beans was examined against high-fat diet fed-streptozotocin-induced …

Gallic acid improves glucose tolerance and triglyceride concentration in diet-induced obesity mice

EJ Bak, J Kim, S Jang, GH Woo, HG Yoon… - … journal of clinical and …, 2013 - Taylor & Francis
Gallic acid, a phenolic phytochemical, has been shown to exert a variety of effects, including
anti-oxidative, anti-carcinogenic, anti-allergic, and anti-inflammatory effects. In this study, we …

[HTML][HTML] Modulation of hyperglycemia and dyslipidemia in experimental type 2 diabetes by gallic acid and p-coumaric acid: The role of adipocytokines and PPARγ

A Abdel-Moneim, SM Abd El-Twab, AI Yousef… - Biomedicine & …, 2018 - Elsevier
There are many indications that confirm the vital role of adipocytokines and PPARγ in
diabetics. Hence, the current investigation aimed to study the modulatory effects of gallic …

Insulin mimetic impact of Catechin isolated from Cassia fistula on the glucose oxidation and molecular mechanisms of glucose uptake on Streptozotocin-induced …

P Daisy, K Balasubramanian, M Rajalakshmi, J Eliza… - Phytomedicine, 2010 - Elsevier
Diabetes mellitus is the most common and serious metabolic disorder among people all
over the world. Many plants have successfully been used to overcome this problem. Cassia …

Gallic acid ameliorates hyperglycemia and improves hepatic carbohydrate metabolism in rats fed a high-fructose diet

DW Huang, WC Chang, JSB Wu, RW Shih, SC Shen - Nutrition research, 2016 - Elsevier
Herein, we investigated the hypoglycemic effect of plant gallic acid (GA) on glucose uptake
in an insulin-resistant cell culture model and on hepatic carbohydrate metabolism in rats …

[HTML][HTML] Gallic acid ameliorated impaired lipid homeostasis in a mouse model of high-fat diet—and streptozotocin-induced NAFLD and diabetes through Improvement …

J Chao, HY Cheng, ML Chang, SS Huang… - Frontiers in …, 2021 - frontiersin.org
Gallic acid (GA) is a simple polyphenol found in food and traditional Chinese medicine.
Here, we determined the effects of GA administration in a combined mouse model of high-fat …

Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling

BC Variya, AK Bakrania, SS Patel - Phytomedicine, 2020 - Elsevier
Background Nature has gifted a variety of vital phytochemicals having potential therapeutic
application against various ailments. Emblica officinalis (E. officinalis), an ancient plant, has …

Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in …

GR Gandhi, A Stalin, K Balakrishna… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: The present study was aimed at isolating an antidiabetic molecule from a
herbal source and assessing its mechanism of action. METHODS: Embelin, isolated from …

[HTML][HTML] Guava leaf inhibits hepatic gluconeogenesis and increases glycogen synthesis via AMPK/ACC signaling pathways in streptozotocin-induced diabetic rats

R Vinayagam, M Jayachandran, SSM Chung… - Biomedicine & …, 2018 - Elsevier
Psidium guajava (PG) is a short shrub or tree cultivated in tropical and subtropical regions
around the world. The leaf extract of PG (guava leaf) has been used historically to cure many …

Gallic acid regulates body weight and glucose homeostasis through AMPK activation

KV Doan, CM Ko, AW Kinyua, DJ Yang, YH Choi… - …, 2015 - academic.oup.com
Abstract Gallic acid [3, 4, 5-trihydroxybenzoic acid (GA)], a natural phytochemical, is known
to have a variety of cellular functions including beneficial effects on metabolic syndromes …