The pedunculopontine tegmental nucleus: where the striatum meets the reticular formation

WL Inglis, P Winn - Progress in neurobiology, 1995 - Elsevier
The pedunculopontine tegmental nucleus (PPTg) contains a population of cholinergic
neurons (the Ch5 group) and non-cholinergic neurons. There appears to be functional …

On the relationships between the striatum and the pedunculopontine tegmental nucleus

P Winn, VJ Brown, WL Inglis - Critical Reviews™ in …, 1997 - dl.begellhouse.com
In this essay we consider the role of the pedunculopontine tegmental nucleus as a striatal
output station. We review the relevant anatomical, electrophysiological, behavioral, and …

How best to consider the structure and function of the pedunculopontine tegmental nucleus: evidence from animal studies

P Winn - Journal of the neurological sciences, 2006 - Elsevier
This review presents the hypothesis that the best way to consider the pedunculopontine
tegmental nucleus is by analogy with the substantia nigra. The substantia nigra contains two …

The pedunculopontine tegmental nucleus: a role in cognitive processes?

T Sleekier, W Inglis, P Winn, A Sahgal - Brain Research Reviews, 1994 - Elsevier
The cholinergic pedunculopontine tegmental nucleus, located in the brainstem and part of
the reticular formation, has been traditionally linked to motor function, arousal and sleep. Its …

Experimental studies of pedunculopontine functions: are they motor, sensory or integrative?

P Winn - Parkinsonism & related disorders, 2008 - Elsevier
The pedunculopontine tegmental nucleus (PPTg) is involved in Parkinson's disease and has
become a therapeutic target. However, its normal functions are uncertain: are they motor …

Pedunculopontine nucleus and basal ganglia: distant relatives or part of the same family?

J Mena-Segovia, JP Bolam, PJ Magill - Trends in neurosciences, 2004 - cell.com
The basal ganglia are more highly interconnected with the pedunculopontine tegmental
nucleus (PPN) than with any other brain region. Regulation and relay of basal ganglia …

Pedunculopontine nucleus: functional organization and clinical implications

EE Benarroch - Neurology, 2013 - AAN Enterprises
The pedunculopontine tegmental nucleus (PPN) is a neurochemically and functionally
heterogeneous structure that occupies a strategic position in the dorsal tegmentum of the …

Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei

HJ Lee, DB Rye, AE Hallanger… - Journal of …, 1988 - Wiley Online Library
Previous studies have suggested that the pedunculopontine tegmental nucleus (PPTn) is
reciprocally connected with extrapyramidal motor system nuclei (EPMS) whereas other …

T he pedunculopontine tegmental nucleus—A functional hypothesis from the comparative literature

NK Gut, P Winn - Movement Disorders, 2016 - Wiley Online Library
We present data from animal studies showing that the pedunculopontine tegmental nucleus—
conserved through evolution, compartmentalized, and with a complex pattern of inputs and …

Rethinking the pedunculopontine nucleus: from cellular organization to function

J Mena-Segovia, JP Bolam - Neuron, 2017 - cell.com
The pedunculopontine nucleus (PPN) has long been considered an interface between the
basal ganglia and motor systems, and its ability to regulate arousal states puts the PPN in a …