Tumor-derived small extracellular vesicles in cancer invasion and metastasis: molecular mechanisms, and clinical significance

C Zhang, C Qin, S Dewanjee, H Bhattacharya… - Molecular Cancer, 2024 - Springer
The production and release of tumor-derived small extracellular vesicles (TDSEVs) from
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …

Role of tumor‑derived extracellular vesicles in cancer progression and their clinical applications

F Qiao, P Pan, J Yan, J Sun… - International …, 2019 - spandidos-publications.com
Extracellular vesicles (EVs), including micro‑vesicles and exosomes, are heterogeneous
small membranous vesicles shed from the surface of myriad cells and are crucial in …

Extracellular vesicles in cancer metastasis: Potential as therapeutic targets and materials

A Kogure, Y Yoshioka, T Ochiya - International journal of molecular …, 2020 - mdpi.com
The vast majority of cancer-related deaths are due to metastasis of the primary tumor that
develops years to decades after apparent cures. However, it is difficult to effectively prevent …

Small extracellular vesicles and metastasis—Blame the messenger

T Seibold, M Waldenmaier, T Seufferlein, T Eiseler - Cancers, 2021 - mdpi.com
Simple Summary Due to their systemic nature, metastatic lesions are a major problem for
curative cancer treatment. According to a common model for metastasis, tumor cells …

Pathological and therapeutic significance of tumor-derived extracellular vesicles in cancer cell migration and metastasis

GL Liguori, V Kralj-Iglič - Cancers, 2023 - mdpi.com
Simple Summary Cancer metastasis accounts for almost 90% of cancer deaths worldwide.
The efficiency of current surgical, radiotherapeutic, and chemotherapeutic approaches is …

[HTML][HTML] Tumor-derived extracellular vesicles: Potential tool for cancer diagnosis, prognosis, and therapy

T Saleem, A Sumrin, M Bilal, H Bashir… - Saudi Journal of …, 2022 - Elsevier
Various types of cancer pose a notable threat to human health globally. To date, many
researchers have undertaken the search for anticancer therapies. However, many …

How cancer cells dictate their microenvironment: present roles of extracellular vesicles

Y Naito, Y Yoshioka, Y Yamamoto, T Ochiya - Cellular and Molecular Life …, 2017 - Springer
Intercellular communication plays an important role in cancer initiation and progression
through secretory molecules, including growth factors and cytokines. Recent advances have …

[HTML][HTML] Small extracellular vesicles: non-negligible vesicles in tumor progression, diagnosis, and therapy

X Zhou, Y Jia, C Mao, S Liu - Cancer Letters, 2023 - Elsevier
Small extracellular vesicles (sEVs) such as exosomes are nanoscale membranous particles
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …

Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
Background Studies have recently revealed that almost every type of cells including tumor
cells abundantly release small vesicles known as extracellular vesicles (EVs) into the …

Extracellular vesicles as mediators of cancer disease and as nanosystems in theranostic applications

R Burgos-Ravanal, A Campos, MC Díaz-Vesga… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is the second leading cause of death in humans, and in 2020, 9.8
million cancer-related deaths were reported worldwide. In the last 20 years, it has become …