Engineering complex tissues requires a precisely formulated combination of cells,
spatiotemporally released bioactive factors, and a specialized scaffold support system …

The state-of-the-art approach to regenerating different tissues and organs is tissue
engineering which includes the three parts of stem cells (SCs), scaffolds, and growth factors …

Engineering craniofacial bone tissues is challenging due to their complex structures. Current
standard autografts and allografts have many drawbacks for craniofacial bone tissue …

Conditions such as congenital anomalies, cancers, and trauma can all result in devastating
deficits of bone in the craniofacial skeleton. This can lead to significant alteration in function …

Oral Diseases (2010) 16, 709–716 Although advances in surgical techniques and bone
grafting have significantly improved the functional and cosmetic restoration of craniofacial …

Tissue engineering and regenerative medicine is an exciting research area that aims at
regenerative alternatives to harvested tissues for transplantation. Biomaterials play a pivotal …

Injectable scaffolds are appealing for tissue regeneration because they offer many
advantages over pre-formed scaffolds. This article provides a comprehensive review of the …

The craniofacial region consists of several different tissue types. These tissues are quite
commonly affected by traumatic/pathologic tissue loss which has so far been traditionally …

Current reconstructive approaches to large craniofacial skeletal defects are often
complicated and challenging. Critical-sized defects are unable to heal via natural …

The craniofacial region contains skin, bones, cartilage, the temporomandibular joint (TMJ),
teeth, periodontal tissues, mucosa, salivary glands, muscles, nerves, and blood vessels …