The adverse outcome pathway (AOP) approach combines patterns of molecular events
across levels of biological organization and complex endpoints such as reproduction …

Anthropogenic surface and ground water contamination by chemicals is a global problem,
and there is an urgent need to develop tools to identify and elucidate biological effects …

The extent of our knowledge on the number of chemical compounds related to
anthropogenic activities that can cause damage to the environment and to organisms is …

On the 30th anniversary of the journal, I provide a perspective on some of the questions and
opportunities for new understanding that will interest aquatic toxicologists during the next 30 …

An emerging environmental pollutant may have a greater impact on phenotypic plasticity
than its direct toxicity, causing maladaptive responses of organisms to their current …

Ecotoxicogenomic approaches to environmental monitoring provide holistic information,
offer insight into modes of action, and help to assess the causal agents and potential toxicity …

Anthropogenically sourced chemicals are commonly released into aquatic habitats where
they can have a multitude of detrimental effects on organisms and ecosystems. Aquatic …

Environmental endocrine disruptors (EDC's) are environmental contaminants that act by
alteration of one or more aspects of the endocrine system of affected individuals. Though …

The expanding diversity and ever increasing amounts of man-made chemicals discharged
to the environment pose largely unknown hazards to ecosystem and human health. The …

Knowledge of possible toxic mechanisms (or modes) of action (MOA) of chemicals can
provide valuable insights as to appropriate methods for assessing exposure and effects …