Impact of spatial and temporal stability of flow vortices on vascular endothelial cells

K Sunderland, W Jia, W He, J Jiang, F Zhao - Biomechanics and modeling …, 2023 - Springer
Abstract Purpose: Intracranial aneurysms (IAs) are pathological dilations of cerebrovascular
vessels due to degeneration of the mechanical strength of the arterial wall, precluded by …

Impact of hemodynamic vortex spatial and temporal characteristics on analysis of intracranial aneurysms

KW Sunderland - 2021 - search.proquest.com
Subarachnoid hemorrhage is a potentially devastating pathological condition in which
bleeding occurs into the space surrounding the brain. One of the prominent sources of …

Disturbed fluid flow reinforces endothelial tractions and intercellular stresses

J Wu, RL Steward Jr - Journal of Biomechanics, 2024 - Elsevier
Disturbed fluid flow is well understood to have significant ramifications on endothelial
function, but the impact disturbed flow has on endothelial biomechanics is not well …

[PDF][PDF] Linking Wall Shear Stress and Vorticity Topologies: Towards a Unified Theory of Cardiovascular Flow Disturbances

U Morbiducci - researchgate.net
Broadening current knowledge about the complex relationship at the blood-vessel wall
interface is a main challenge in hemodynamics research. Moving from the consideration that …

Linking wall shear stress and vorticity topologies: Toward a unified theory of cardiovascular flow disturbances

V Mazzi, D Gallo, K Calò, DA Steinman… - Physics of …, 2024 - pubs.aip.org
Broadening current knowledge about the complex relationship at the blood-vessel wall
interface is a main challenge in hemodynamics research. Moving from the consideration that …

[图书][B] Vortex-based spatiotemporal characterization of nonlinear flows

GA Byrne - 2013 - ui.adsabs.harvard.edu
Although the ubiquity of vortices in nature has been recognized by artists for over seven
centuries, it was the work of artist and scientist Leonardo da Vinci that provided the …

High fluid shear stress and spatial shear stress gradients affect endothelial proliferation, survival, and alignment

JM Dolan, H Meng, S Singh, R Paluch… - Annals of biomedical …, 2011 - Springer
Cerebral aneurysms develop near bifurcation apices, where complex hemodynamics occur:
Flow impinges on the apex, accelerates into branches, then slows again distally, creating …

[PDF][PDF] Experimental and numerical analyses of the hemodynamics impact on real intracranial aneurysms: a particle tracking velocimetry approach

A Souza, D Lopes, S Souza, J Ribeiro, R Lima… - researchgate.net
This study investigates the impact of hemodynamics on real intracranial aneurysms (IAs)
using experiments and computational fluid dynamics (CFD) simulations. A particle tracking …

An in vitro device for evaluation of cellular response to flows found at the apex of arterial bifurcations

Z Zeng, BJ Chung, M Durka, AM Robertson - … Galdi on the Occasion of his …, 2010 - Springer
Intracranial aneurysms (ICA) are abnormal dilations of the cerebral arteries, most commonly
located at the apices of bifurcations. The ability of the arterial wall, particularly the …

Endothelial responses to curvature-induced flow patterns in engineered cerebral aneurysms

CJ Mandrycky, AN Abel, S Levy… - Journal of …, 2023 - asmedigitalcollection.asme.org
Hemodynamic factors have long been associated with clinical outcomes in the treatment of
cerebral aneurysms. Computational studies of cerebral aneurysm hemodynamics have …