The development of efficient processes for the preparation of structurally diverse axially
chiral biaryls has been an important goal in synthetic organic chemistry and asymmetric …

Diaryl ethers are important structural motifs widely found in bioactive natural products,
ligands, and catalysts. While there are a variety of methods available to generate diaryl …

The first catalytic asymmetric construction of axially chiral 4-aryl α-carboline skeletons has
been accomplished through an N-heterocyclic carbene (NHC)-catalyzed atroposelective …

Atropoisomeric biaryl motifs are widely found in natural products and bioactive compounds
as well as chiral catalysts and ligands. Various efficient approaches have been disclosed for …

Axially chiral molecules bearing multiple stereogenic axes are of great importance in the
field of organic chemistry. However, the efficient construction of atropisomers featuring two …

Axially chiral biaryl scaffolds are vital in natural products, pharmaceuticals, and asymmetric
synthesis. Catalytically atroposelective ring-opening of configurationally labile compounds …

Molecules containing an atropisomeric C–N biaryl axis are gaining increasing attention in
catalytic and medicinal chemistry. Despite this rising interest, relatively few approaches …

Axially chiral diaryl ethers are present in numerous natural products and bioactive
molecules. However, only few catalytic enantioselective approaches have been established …

Axially chiral diarylamine atropisomers represent a distinct category characterized by two
contiguous chiral C–N axes, which exhibit a significantly lower racemization barrier due to …

N− C Biaryl atropisomers are prevalent in natural products and bioactive drug molecules.
However, the enantioselective synthesis of such molecules has not developed significantly …