Background Oxidation, inflammation, and apoptosis are three critical factors for the
pathogenic mechanism of cerebral ischemia/reperfusion (I/R) injury. Curcumin exhibits …

Reperfusion is the only approved therapy for acute ischemic stroke; however, it can cause
excessive inflammation responses and aggravate brain damage. Therefore, supplementary …

The aim of the present study was to investigate the protective effects of curcumin and its
effect on the methyl ethyl ketone/extracellular signal regulated kinase/cAMP‑response …

Abstract Background and Purpose Curcumin, a natural antioxidant isolated from Curcuma
longa, has been reported to exert neuroprotective effect in animal models of ischemic stroke …

Abstract Toll-like receptors 2 and 4 (TLR2/4) and the downstream nuclear factor-kappa B
(NF-κB) signaling pathway, which mediate the inflammatory reaction in cerebral ischemia …

Inflammatory reactions play a key role in the cerebral injury after stroke or other ischemic
brain diseases. Curcumin, which is extracted from herb turmeric, has been reported to have …

Oxidative damage plays a critical role in many diseases of the central nervous system. This
study was conducted to determine the molecular mechanisms involved in the putative anti …

The blood‑brain barrier (BBB) is critical for proper cerebral homeostasis and its dysfunction
during ischemic stroke can result in significant neurological injury. The major goal of the …

Curcumin, a member of the curcuminoid family of compounds, is a yellow colored phenolic
pigment obtained from the powdered rhizome of C. longa Linn. Recent studies have …

Curcumin (Cur) is the active component in Curcuma longa, and it has been reported to
exhibit a variety of biological effects such as anti-inflammation and anti-oxidation. This study …