We have previously reported that chronic imipramine and electroconvulsive treatments
increase the α 1A-adrenoceptor (but not the α 1B subtype) mRNAlevel and the receptor …

α1-Adrenoceptors have been implicated in the mechanism of action of antidepressants, but
their action on specific receptor subtypes was rarely reported. We compared now the action …

Repeated electroconvulsive shock (ECS) was administered to rats previously injected with
DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride), a noradrenergic …

The relative numbers of pre-and postsynaptic α 2-adrenoceptors were determined in various
rat brain regions after short-term DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine) …

The aim of the present study was to examine the effect of chronic antidepressants treatment
on the density of α 1-adrenoceptor (AR) subtypes in rat brain. Density of total α 1 and α 1A …

Abstract Treatment of rats with electroconvulsive shock once daily for 10–12 days increased
the density of α 1-adrenoceptors labeled by [3 H] prazosin in homogenates of frontal …

We previously reported that chronic treatment with imipramine and electroconvulsive shock
up-regulate the density and α)-adrenergic receptor (α)-AR) mRNA level in the rat prefrontal …

The effect of repeated treatment with imipramine, citalopram and ECS on the density of α1‐
adrenoceptors in the cerebral cortex of rats with a dopaminergic lesion was studied …

ObjectivesDisturbances in the noradrenergic system, including alterations in the densities of
α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this …

Evidence suggests that depression is associated with an increase in the high-affinity
conformation of the α2-adrenoceptors in human brain. Such enhanced α2-adrenoceptor …