The targeted delivery of potent cytotoxic agents has emerged as a promising strategy for the
treatment of cancer and other serious conditions. Traditionally, antibodies against markers of …

DNA-encoded chemical libraries represent a novel avenue for the facile discovery of small
molecule ligands against target proteins of biological or pharmaceutical importance. Library …

The encoding of chemical compounds with amplifiable DNA tags facilitates the discovery of
small-molecule ligands for proteins. To investigate the impact of stereo-and regiochemistry …

The discovery and development of novel drugs for the multitude of targets originating from
functional genomic research is a challenging task. While antibodies can nowadays be …

The selection of DNA‐encoded libraries against biological targets has become an important
discovery method in chemical biology and drug discovery, but the requirement of modified …

The identification of specific binding molecules is a central problem in chemistry, biology
and medicine. Therefore, technologies, which facilitate ligand discovery, may substantially …

The high‐throughput synthesis and screening of compound libraries hold tremendous
promise for drug discovery and powerful methods for both solid‐phase and solution‐phase …

DNA-encoded chemical libraries (DELs) have recently emerged and become an important
technology platform in biomedical research and drug discovery. DELs containing large …

The isolation of specific binding molecules is a central problem in the drug discovery
process and might be useful for the elucidation of the biological function of proteins …

Methods for the rapid and inexpensive discovery of hit compounds are essential for
pharmaceutical research and DNA‐encoded chemical libraries represent promising tools for …