Arsenic metabolism and thioarsenicals

K Rehman, H Naranmandura - Metallomics, 2012 - academic.oup.com
Arsenic has received considerable attention in the world, since it can lead to a multitude of
toxic effects and has been recognized as a human carcinogen causing cancers. Here, we …

Thiolation in arsenic metabolism: a chemical perspective

C Fan, G Liu, Y Long, B Rosen, Y Cai - Metallomics, 2018 - pubs.rsc.org
In recent years, methylated thioarsenicals have been widely detected in various biological
and environmental matrices, suggesting their broad involvement and biological importance …

Thiolated arsenicals in arsenic metabolism: Occurrence, formation, and biological implications

Y Sun, G Liu, Y Cai - Journal of Environmental Sciences, 2016 - Elsevier
Arsenic (As) is a notoriously toxic pollutant of health concern worldwide with potential risk of
cancer induction, but meanwhile it is used as medicines for the treatment of different …

The duality of arsenic metabolism: impact on human health

MA El-Ghiaty, AOS El-Kadi - Annual review of pharmacology …, 2023 - annualreviews.org
Arsenic is a naturally occurring hazardous element that is environmentally ubiquitous in
various chemical forms. Upon exposure, the human body initiates an elimination pathway of …

Arsenic: toxic effects and remediation

SI Siddiqui, SA Chaudhry - Advanced materials for wastewater …, 2017 - Wiley Online Library
Arsenic is associated with cancerous and non-cancerous human diseases. Arsenic from
drinking water is the most common source of human exposure and it has becomes major …

Speciation of key arsenic metabolic intermediates in human urine

XC Le, X Lu, M Ma, WR Cullen, HV Aposhian… - Analytical …, 2000 - ACS Publications
Biomethylation is the major human metabolic pathway for inorganic arsenic, and the
speciation of arsenic metabolites is essential to a better understanding of arsenic …

[HTML][HTML] Metabolism, toxicity and anticancer activities of arsenic compounds

I Khairul, QQ Wang, YH Jiang, C Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
A variety of studies indicated that inorganic arsenic and its methylated metabolites have
paradoxical effects, namely, carcinogenic and anticancer effects. Epidemiological studies …

Arsenic toxicity and potential mechanisms of action

MF Hughes - Toxicology letters, 2002 - Elsevier
Exposure to the metalloid arsenic is a daily occurrence because of its environmental
pervasiveness. Arsenic, which is found in several different chemical forms and oxidation …

Importance of being thiomethylated: formation, fate, and effects of methylated thioarsenicals

QQ Wang, DJ Thomas… - Chemical research in …, 2015 - ACS Publications
Although inorganic arsenic has long been recognized as a potent toxicant and carcinogen in
humans, recent evidence shows that at least some of its effects are mediated by methylated …

The relevance of arsenic speciation analysis in health & medicine

RK Virk, R Garla, N Kaushal, MP Bansal, ML Garg… - Chemosphere, 2023 - Elsevier
Long term exposure to arsenic through consumption of contaminated groundwater has been
a global issue since the last five decades; while from an alternate standpoint, arsenic …