[HTML][HTML] Adhesion molecules in peritoneal dissemination: function, prognostic relevance and therapeutic options

N Sluiter, E de Cuba, R Kwakman, G Kazemier… - Clinical & experimental …, 2016 - Springer
Peritoneal dissemination is diagnosed in 10–25% of colorectal cancer patients. Selected
patients are treated with cytoreductive surgery and hyperthermic intraperitoneal …

Understanding molecular mechanisms in peritoneal dissemination of colorectal cancer: future possibilities for personalised treatment by use of biomarkers

EMV De Cuba, R Kwakman, M Van Egmond… - Virchows Archiv, 2012 - Springer
When colorectal cancer (CRC) metastasizes, this is mostly to the liver via the portal
circulation. In addition, 10–25% of CRC patients eventually show metastases in the …

ICAM-1 mediated tumor-mesothelial cell adhesion is modulated by IL-6 and TNF-α: a potential mechanism by which surgical trauma increases peritoneal metastases

P Ziprin, PF Ridgway, KLM Pfistermüller… - Cell communication & …, 2003 - Taylor & Francis
Peritoneal metastases frequently occur in different gastrointestinal cancers and have a poor
prognosis. It is known that surgical injury promotes tumor growth and local recurrence rates …

Role of integrin α1 subunits in gastric cancer patients with peritoneal dissemination

K Fukuda, Y Saikawa, H Yagi… - Molecular …, 2012 - spandidos-publications.com
The interaction between gastric cancer (GC) cells and the peritoneum is a critical event in
peritoneal dissemination. The molecular mechanisms of this dissemination, however …

ICAM-1 mediated peritoneal carcinomatosis, a target for therapeutic intervention

NA Alkhamesi, P Ziprin, K Pfistermuller… - Clinical & experimental …, 2005 - Springer
Abstract Development of peritoneal metastasis is a significant issue in the treatment of
abdominal cancers. Primary interaction between tumour cells and the mesothelium is a vital …

Targeting hyaluronic acid and peritoneal dissemination in colorectal cancer

F Soliman, L Ye, W Jiang, R Hargest - Clinical colorectal cancer, 2022 - Elsevier
Peritoneal metastasis (PM) from colorectal cancer (CRC) carries a significant mortality rate
for patients and treatment is challenging. The development of PM is a multistep process …

A mouse model for peritoneal metastases of colorectal origin recapitulates patient heterogeneity

VP Bastiaenen, CEL Klaver… - Laboratory …, 2020 - nature.com
The peritoneum is a common site of dissemination in patients with colorectal cancer. In order
to identify high-risk patients and improve therapeutic strategies, a better understanding of …

[HTML][HTML] Activated leukocyte cell adhesion molecule (ALCAM), a potential 'seed'and 'soil'receptor in the peritoneal metastasis of gastrointestinal cancers

YM Yang, L Ye, F Ruge, Z Fang, K Ji… - International Journal of …, 2023 - mdpi.com
Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a cell–cell adhesion
protein conferring heterotypic and homotypic interactions between cells of the same type …

Colorectal peritoneal metastases: pathogenesis, diagnosis and treatment options–an evidence‐based update

V Narasimhan, G Ooi, M Michael… - ANZ journal of …, 2020 - Wiley Online Library
Peritoneal metastases confer the worst survival among all sites in patients with metastatic
colorectal cancer. They develop largely through transcoelomic spread, with a sequence of …

[HTML][HTML] Development of the peritoneal metastasis: a review of back-grounds, mechanisms, treatments and prospects

K Ren, X Xie, T Min, T Sun, H Wang, Y Zhang… - Journal of Clinical …, 2022 - mdpi.com
Peritoneal metastasis is a malignant disease which originated from several gastrointestinal
and gynecological carcinomas and has been leading to a suffering condition in patients for …