Derangements in cerebrovascular structure and function can impair cognitive performance
throughout ageing and in cardiometabolic disease states, thus increasing dementia risk …

Increasing the lifespan of a population is often a marker of a country's success. With the
percentage of the population over 65 yr of age expanding, managing the health and …

Background Aging and physical inactivity are associated with declines in some cognitive
domains and cerebrovascular function, as well as an elevated risk of cerebrovascular …

The number of adults with Alzheimer's disease (AD) or related dementia is expected to
increase exponentially. Interventions aimed to reduce the risk and progression of AD and …

Cognitive performances are tightly associated with the maximal aerobic exercise capacity,
both of which decline with age. The benefits on mental health of regular exercise, which …

When the 21st century dawned, there were approximately 600 million persons aged 60 yr
and older worldwide. By the middle of this century, this will more than triple to 2 billion …

Human aging is accompanied by both vascular and cognitive changes. Although arteries
throughout the body are known to become stiffer with age, this vessel hardening is believed …

Background Physical activity may attenuate age-related cognitive decline by improving
cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic …

Exercise training promotes extensive cardiovascular changes and adaptive mechanisms in
both the peripheral and cerebral vasculature, such as improved organ blood flow, induction …

Objective To test the hypothesis that aerobic exercise is associated with improvements in
cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged …